sirtuins
English translation: 沉默信息调控因子2
| 02:49 Sep 7, 2008 |
| Chinese to English translations [PRO] Science - Biology (-tech,-chem,micro-) | |||||||
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|  Selected response from: calpain China Local time: 23:24 | ||||||
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| Summary of answers provided | ||||
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| 4 | 组蛋白脱乙酰基酶 |
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| 4 | 去乙酰化酶酵素 |
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| 4 | 去乙酰化酶 |
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| 4 | 建议译名：寿调因或寿调蛋白 |
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| 3 | 沉默信息调控因子2 |
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| Discussion entries: 2 | |
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Answers
30 mins confidence: 
组蛋白脱乙酰基酶 Explanation: http://baike.baidu.com/view/1440516.html 这是百度里的译法。是否广为接受，尚不得而知。 |
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7 hrs confidence:
去乙酰化酶酵素 Explanation: Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases/mono-ADP-ribosyltransferases found in organisms ranging from bacteria to humans. Sir蛋白質與基因的沉寂有關，事實上，SIR就是「沉寂資訊的調節者」（silent information regulator）的英文縮寫。Sir2是負責移除組織蛋白上乙醯標記的酵素之一，但我們發現Sir2作用的獨特之處，是其酵素活性絕對需要一個無所不在的小分子：菸鹼醯胺腺嘌呤二核酸（NAD），NAD是許多細胞代謝反應的輔。發現Sir2和NAD的關聯讓我們非常興奮，因為它讓Sir2的活性與代謝連接了起來，因此可解釋飲食熱量限制與老化的關係。 |
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9 hrs confidence:
沉默信息调控因子2 Explanation: 首先看下wiki的解释 Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases/mono-ADP-ribosyltransferases found in organisms ranging from bacteria to humans. 可见Silent information regulator 2 (Sir2) proteins是sirtuin的全名。虽然它有脱乙酰酶的活性，但脱乙酰化酶有许多种，它只是其中的一种。因此单用脱乙酰酶来翻译sirtuin似乎不太全面。 Reference: http://en.wikipedia.org/wiki/Sirtuin |
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1 day 2 hrs confidence:
去乙酰化酶 Explanation: 去乙酰化酶 其实不如就叫“抗衰老酶“好了，多明了易懂呵，可以价格括号里写上英文名，就不会错了。 |
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23 days confidence:
建议译名：寿调因或寿调蛋白 Explanation: Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases/mono-ADP-ribosyltransferases found in organisms ranging from bacteria to humans. Silent information regulator 2国内文献已有中文名称： google发现(08年9月30日10:50) 约有59项符合"沉默信息调节因子2"的查询结果 共有 7 项符合"沉默信息调控因子2"的查询结果 sirtuins 是“Silent information regulator 2 (Sir2) proteins”的缩写，可见是取前面三个单词的首字母，2 取其读音[tu],再加上proteins的'ins"来构成。 未见sirtuins的中文译名，本人首次建议其中文译名如下： 已知Silent information regulator 2 (Sir2) proteins”是一种调节蛋白，具有抗寿命、延长寿命的作用，因此，其缩写词sirtuins可以译成：寿调因或寿调蛋白。 “寿调因”完全与sirtuins谐音，同时望文生义，容易理解是“调节寿命的因子”，与sirtuins原义吻合。 “寿调蛋白”则是音义结合的译法，表明sirtuins是蛋白质，具有“调节寿命”的作用。 |
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