conformational change

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15:54 May 2, 2010
English to Catalan translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics
English term or phrase: conformational change
Definition from Biochemical Society:
Large, medium or small adjustment to the molecular shape/dynamics of a protein that may follow a change in environment or the specific recognition of another molecule.

Example sentence(s):
  • These observations indicate that heparin, in addition to causing aggregation, also induces a conformational change in tau in which reactive groups are unmasked or move closer leading to the DSS cross-linking of 72- and 83-kDa species. jbc online
  • At low pH, the hemagglutinin (HA) of influenza virus undergoes an irreversible conformational change that potentiates its essential membrane fusion function. The Rockefeller University Press
  • To develop the antibody chip for detecting the Bax conformational change, we immobilized Bax monoclonal antibody 6A7, which recognizes only a conformationally changed Bax protein on a gold surface. Elsevier Inc.
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Summary of translations provided
5canvi conformacional
Gemma Sanza Porcar


Discussion entries: 1





  

Translations offered


35 days   confidence: Answerer confidence 5/5
canvi conformacional


Definition from own experience or research:
Canvi de l´estructura molecular com a conseqüència de la rotació del seu/seus enllaços.

Example sentence(s):
  • El canvi de conformació a aquest darrer estat ha d´explicar la cooperativitat en la unió del O2. La fixació del mateix O2 al grup hemo es la causa del <b>canvi conformacional</b>. - Fonaments de bioquímica Juli Peretó (U  
  • Al llarg de la contracció, en rebre el senyal nerviós, s’allibera calci cap al sarcoplasma; aquest calci s’uneix immediatament als centres d’unió del calci a la troponina, induint un <b>canvi conformacional</b> que permet que els caps d’actina i miosina s’uneixin formant un angle, aproximadament, de 90º. L’alliberació de la molècula de fòsfor del complex actina-miosina-ADP comporta un <b>canvi conformacional</b> que fa lliscar l’actina (cop de força) adoptant un angle de 45º sobre la miosina. - Societat Catalana de Cardiologia  
  • La unió del lligand al receptor provocarà un <b>canvi conformacional</b> en aquest que li permetrà la interacció amb la proteïna G. Generalment, aquest <b>canvi conformacional</b> afecta la conformació de les nanses C-II i C-III del receptor, que presenten un paper important en el reconeixement i en l’activació de la proteïna G. - TDR  
Gemma Sanza Porcar
Spain
Local time: 01:06
Native speaker of: Native in SpanishSpanish, Native in CatalanCatalan
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