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vitamin k-dependent plasma glycoprotein

French translation: - Glycoprotéine plasmatique vitamine K-dépendante

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00:54 May 17, 2020
English to French translations [PRO]
COVID-19 - Science - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: vitamin k-dependent plasma glycoprotein
Definition from Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z

Example sentence(s):
  • This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. National Center for Biotechnology Info.
  • Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. Research Gate
  • Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. The JBC
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French translation:- Glycoprotéine plasmatique vitamine K-dépendante
Definition:
OU : Glycoprotéine plasmatique dépendante de la vitamine K

Glycoprotéine plasmatique vitamine K-dépendante, cofacteur de la protéine C activée. - Son activité de cofacteur est régulée par la thrombine, qui scinde la protéine S.
Selected response from:

Hugues Roumier
France
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
4 +3- Glycoprotéine plasmatique vitamine K-dépendante
Hugues Roumier


  

Translations offered


3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
- Glycoprotéine plasmatique vitamine K-dépendante


Definition from tenma123:
OU : Glycoprotéine plasmatique dépendante de la vitamine K

Glycoprotéine plasmatique vitamine K-dépendante, cofacteur de la protéine C activée. - Son activité de cofacteur est régulée par la thrombine, qui scinde la protéine S.

Example sentence(s):
  • La protéine C est une glycoprotéine vitamine K-dépendante du plasma sanguin. Elle est synthétisée par le foie en tant que proenzyme inactive qui, sous l'influence d'un complexe thrombine-thrombomoduline est convertie en forme active. La protéine C activée - enzyme inactivant sélectivement anticoagulant facteurs Va et VIIIa par leur hydrolyse en présence de calcium ionisé, les phospholipides et les cofacteurs - protéine S, empêchant ainsi le transfert de la prothrombine en thrombine. - I live - Sante  
  • (...) est une glycoprotéine à simple chaîne, vitamine K dépendante, de PM (..) - hematoweb  
  • Glycoprotéine plasmatique vitamine K-dépendante, cofacteur de la protéine C activée. - PDF Maladies thrombo-emboliques récidiv  

Explanation:
Sérine protéases Facteurs vitamine K dépendants
Physiologie et exploration de l’hémostase : http://l2bichat2018-2019.weebly.com/uploads/1/1/2/5/11258763...

Terme aussi trouve : https://www.eurofins-biomnis.com/referentiel/liendoc/precis/...






Hugues Roumier
France
Local time: 05:13
Native speaker of: Native in FrenchFrench
PRO pts in category: 60

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Christine HOUDY: Les nouvelles propriétés thérapeutiques de la vitamine K dumas.ccsd.cnrs.fr › dumas-01825863 › document PDF 26 juin 2018 - Relation entre les protéines Vitamine K Dépendantes et la calcification ... en vitamine K2 et/ou en vitamine D sur le taux plasmati
4 hrs
Yes  Lionel-N
5 hrs
Yes  Bridget Jean: La protéine C est une protéine plasmatique vitamine K dépendante qui régule la coagulation en inhibant les facteurs Va et VIIIa et permet de limiter l’extension du thrombus. De nombreuses études cliniques ont montré qu’un déficit en protéine C (acquis ou
1 day 4 hrs
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