disruptive

14:16 Dec 18, 2018
English to German translations [PRO]
Medical - Biology (-tech,-chem,micro-) / Onkologie Biochemie
English term or phrase: disruptive
Ad5-PPE-1-3X-fas-chimera (SEQ ID NO: 19) is a vascular disruptive gene therapeutic, consisting of a non-replicating adenovirus vector (Ad5, E1 deleted) which contains a modified murine pre-proendothelin promoter (PPE-1-3x, SEQ ID NO: 18) and a fas-chimera transgene [Fas and human tumor necrosis factor (TNF) receptor] (SEQ ID NO: 9).

Bin mir nicht ganz sicher, wie "disruptive" hier zu verstehen ist
Christine Matschke
Germany
Local time: 21:22


Summary of answers provided
4gefäßzerstörend
gofink
3 -1revolutionär
Regina Eichstaedter
Summary of reference entries provided
vascular disrupting agent
Oliver Annacker

Discussion entries: 4





  

Answers


2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): -1
revolutionär


Explanation:
revolutionäre Gentherapie


    Reference: http://www.schaffler-verlag.com/pdf-download?pdf=25037
Regina Eichstaedter
Local time: 21:22
Native speaker of: Native in GermanGerman
PRO pts in category: 24

Peer comments on this answer (and responses from the answerer)
disagree  Katja Schoone: Siehe Diskussionsbeitrag./Du hast aber auch disruptive (im Sinne von revolutionär) + Gentherapie nirgends gefunden.
16 hrs
  -> Ich habe lange recherchiert und die Kombination disruptiv (im Sinn von gefäßzerstörend) + Gentherapie nirgends gefunden - ich nehme an, das ist auch das Problem von Christine // doch, im Sinn von revolutionär + Gentherapie ist die Kombination häufig
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1 day 6 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
vascular disruptive
gefäßzerstörend


Explanation:
to the vascular disruptive effect of = auf die gefäßzerstörende Wirkung von - see https://www.linguee.de/deutsch-englisch/search?source=auto&q...

gofink
Austria
Local time: 21:22
Native speaker of: Native in GermanGerman
PRO pts in category: 4
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Reference comments


9 hrs peer agreement (net): +1
Reference: vascular disrupting agent

Reference information:
"A vascular-targeting agent (VTA) or vascular disrupting agent (VDA) is a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis."


    https://en.wikipedia.org/wiki/Vascular-targeting_agent
Oliver Annacker
Sweden
Specializes in field
Native speaker of: German
PRO pts in category: 8

Peer comments on this reference comment (and responses from the reference poster)
agree  Katja Schoone: exactly
8 hrs
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