administrative analysis

German translation: administrative Analyse

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:administrative analysis
German translation:administrative Analyse
Entered by: Cécile Kellermayr

23:01 May 20, 2020
English to German translations [PRO]
Science - Mathematics & Statistics
English term or phrase: administrative analysis
3. Frage zu einem einzigen Satz, der mich einigermaßen fordert ;)

(Berechnungsverfahren im Rahmen einer klinischen Vergleichsstudie)

Under these assumptions and for each [Präparat] combination comparison, 125 deaths at interim analysis for OS and 151 deaths (cumulative 70% out of 215 randomized in each of the comparisons) at final analysis for OS are needed to yield approximately 74% power to detect statistical significance in OS by stratified Log-Rank testing procedure with an overall 2-sided type one error of 0.0499, given 2-sided type error of 0.0001 will be spent on the first administrative analysis of PFS and ORR per investigator assessment.
Cécile Kellermayr
Austria
Local time: 21:35
administrative Zwischenanalyse
Explanation:
There are 2 types of interim analyses: Formal and administrative analyses
cp:
“Interim analyses can be divided into formal and administrative analyses”
https://tinyurl.com/yd8b8lkf

“The aim of a formal interim analysis is to decide on early termination of a planned study if there is compelling evidence of beneficial effectiveness or harmful side effects. The administrative interim analysis is relevant in pharmaceutical cases and is conducted for the reasons external to a trial at the request of regulatory agencies or upper management.”
https://tinyurl.com/ybk574hw


d.h. administrative analysis= administrative interim analysis.

Interim analyses that are conducted for decision making external to the study (e.g. planning of different study) are called administrative analyses.

p. 303 here: https://tinyurl.com/yb8e8wtq

Administrative interim analysis: obtain information on the ongoing study without stopping or modifying it
https://tinyurl.com/y76hjtoq

..und nun auf Deutsch!

Interim analysis= Zwischenanalyse (oder Zwischenauswertung)
Administrative (interim) analysis = administrative Zwischenanalyse

So wie hier:
The administrative interim-analysis of the SCIentinel study confirmed its
feasibility after inclusion of 60 patients (51% of calculated sample size).

Die administrative Zwischenanalyse der SCIentinel-Studie bestätigte die Machbarkeit nach Einschluss von 60 Patienten, was 51% gemäß Fallzahlberechnung darstellt.
https://d-nb.info/111359280X/34
Selected response from:

Johanna Timm, PhD
Canada
Local time: 13:35
Grading comment
Vielen Dank, Johanna!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1administrative Zwischenanalyse
Johanna Timm, PhD


  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
administrative Zwischenanalyse


Explanation:
There are 2 types of interim analyses: Formal and administrative analyses
cp:
“Interim analyses can be divided into formal and administrative analyses”
https://tinyurl.com/yd8b8lkf

“The aim of a formal interim analysis is to decide on early termination of a planned study if there is compelling evidence of beneficial effectiveness or harmful side effects. The administrative interim analysis is relevant in pharmaceutical cases and is conducted for the reasons external to a trial at the request of regulatory agencies or upper management.”
https://tinyurl.com/ybk574hw


d.h. administrative analysis= administrative interim analysis.

Interim analyses that are conducted for decision making external to the study (e.g. planning of different study) are called administrative analyses.

p. 303 here: https://tinyurl.com/yb8e8wtq

Administrative interim analysis: obtain information on the ongoing study without stopping or modifying it
https://tinyurl.com/y76hjtoq

..und nun auf Deutsch!

Interim analysis= Zwischenanalyse (oder Zwischenauswertung)
Administrative (interim) analysis = administrative Zwischenanalyse

So wie hier:
The administrative interim-analysis of the SCIentinel study confirmed its
feasibility after inclusion of 60 patients (51% of calculated sample size).

Die administrative Zwischenanalyse der SCIentinel-Studie bestätigte die Machbarkeit nach Einschluss von 60 Patienten, was 51% gemäß Fallzahlberechnung darstellt.
https://d-nb.info/111359280X/34


Johanna Timm, PhD
Canada
Local time: 13:35
Native speaker of: Native in GermanGerman
PRO pts in category: 4
Grading comment
Vielen Dank, Johanna!

Peer comments on this answer (and responses from the answerer)
agree  Steffen Walter: Oder "Zwischenauswertung". / Stimmt. Wer lesen kann, ... ;-))
1 day 17 hrs
  -> ja, hatte ich auch irgendow erwähnt :-)
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