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  3. Chemistry; Chem Sci/Eng

the eye irritation endpoint

Italian translation: esito/outcome dell\'irritazione oculare

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:the eye irritation endpoint
Italian translation:esito/outcome dell\'irritazione oculare
Entered by: Mario Altare

09:44 Oct 13, 2015
English to Italian translations [PRO]
Science - Chemistry; Chem Sci/Eng / Sostanze naturali complesse
English term or phrase: the eye irritation endpoint
Rosemary

Rosemary oil is a NCS example of which the composition for some of the constituents varies per quality justifying different classifications for ** the eye irritation endpoint **, if the hazard classification is derived by read-across from the classification of the constituents:

The content of constituents classified for eye irritation (H 319) in Rosemary oil can typically vary from 9 to 19 %.

Camphene is the main contributor for this hazard with levels between 2 and 13 %.
Mario Altare
Local time: 14:03
esito/outcome dell'irritazione oculare
Explanation:
"De nizione Outcome, end-point.
Nella metodologia della ricerca clinica possono essere
considerati sinonimi: entrambi hanno il signi cato di “misura di esito”

Selected response from:

giuseppe coroniti
Italy
Local time: 14:03
Grading comment
Grazie mille (anche a Gaetano) :-)
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +2endpoint dell'irritazione oculare
Gaetano Silvestri Campagnano
4esito/outcome dell'irritazione oculare
giuseppe coroniti


  

Answers


31 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
esito/outcome dell'irritazione oculare


Explanation:
"De nizione Outcome, end-point.
Nella metodologia della ricerca clinica possono essere
considerati sinonimi: entrambi hanno il signi cato di “misura di esito”




    Reference: http://www.gimbe.org/report_attivita/pubblicazioni/articoli/...
    https://www.agenziafarmaco.gov.it/ricclin/it/node/265
giuseppe coroniti
Italy
Local time: 14:03
Specializes in field
Native speaker of: Native in ItalianItalian
PRO pts in category: 66
Grading comment
Grazie mille (anche a Gaetano) :-)
Login to enter a peer comment (or grade)

51 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
endpoint dell'irritazione oculare


Explanation:
http://eur-lex.europa.eu/legal-content/IT/TXT/?uri=CELEX:520...

«Gli endpoint ai quali si applica, relativamente al divieto di commercializzazione, la scadenza del 2009 sono: la corrosività cutanea, l'irritazione cutanea, l'assorbimento dermico, la mutagenicità/genotossicità, la fototossicità, la tossicità acuta e l'irritazione oculare[5].»

--------------------------------------------------
Note added at 56 min (2015-10-13 10:40:31 GMT)
--------------------------------------------------

http://reach.sviluppoeconomico.gov.it/faq/faq-information-re...

«Il livello derivato senza effetto (DNEL) per irritazione/corrosione può essere derivato solo se sono disponibili informazioni dose/risposta. Quindi per endpoints come l'irritazione oculare, dove non è possibile derivare un valore di DNEL, è necessario un approccio qualitativo alla valutazione e al controllo di questo rischio.»


Gaetano Silvestri Campagnano
Italy
Local time: 14:03
Native speaker of: Native in ItalianItalian
PRO pts in category: 740

Peer comments on this answer (and responses from the answerer)
agree  Francesco Badolato
19 mins
  -> Grazie mille e Ciao Francesco
agree  Vincenzo Di Maso: "endpoint" è una cosa, "outcome" è un altra
2 days 3 hrs
  -> Grazie mille e Ciao Vincenzo
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