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  3. Chemistry; Chem Sci/Eng

cis retinaldehyde binding protein

Italian translation: proteina legante (11-) cis retinaldeide

15:25 Apr 15, 2019
English to Italian translations [PRO]
Medical - Chemistry; Chem Sci/Eng / Improved modalities for the treatment of degenerative diseases of the retina
English term or phrase: cis retinaldehyde binding protein
Si tratta del brevetto Improved modalities for the treatment of degenerative diseases of the retina.
Nella parte dedicata a RPE defects in Retinitis Pigmentosa trovo:
Two gene defects that case autosomal recessive RP have been found in genes expressed exclusively in RPE: one is due to an RPE protein involved in vitamin A metabolism (cis retinaldehyde binding protein), a second involves another protein unique to RPE, RPE65.
Once rejection is conquered, both of these forms of RP should be treatable immediately by RPE transplantation.

Non trovo una soluzione soddisfacente e non capisco se forse manca una parola prima di cis.
Grazie mille.
Angela Federica Ruspini
Italy
Local time: 23:37
Italian translation:proteina legante (11-) cis retinaldeide
Explanation:
le uniche occorrenze che trovo di cis retinaldeide sono per l'"11-cis retinaldeide"

La defezione di proteine nell’epitelio pigmentato
retinico (EPR) può avere svariate ripercussioni.
Mutazioni nel gene per CRALB (cellular retinaldehyde–
binding protein) portano a un quadro clinico
simile alla RP. Un difetto nel gene per RPE65
provoca, attraverso un processo ancora sconosciuto
(https://retina.ch/wp-content/themes/retina-suisse/retina-jou...

qui hai riferimenti per l'acronimo CRALBP
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC124397/


HIH
Selected response from:

Luca Gentili
Belgium
Local time: 23:37
Grading comment
3 KudoZ points were awarded for this answer



Summary of answers provided
3proteina legante (11-) cis retinaldeide
Luca Gentili


  

Answers


22 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
proteina legante (11-) cis retinaldeide


Explanation:
le uniche occorrenze che trovo di cis retinaldeide sono per l'"11-cis retinaldeide"

La defezione di proteine nell’epitelio pigmentato
retinico (EPR) può avere svariate ripercussioni.
Mutazioni nel gene per CRALB (cellular retinaldehyde–
binding protein) portano a un quadro clinico
simile alla RP. Un difetto nel gene per RPE65
provoca, attraverso un processo ancora sconosciuto
(https://retina.ch/wp-content/themes/retina-suisse/retina-jou...

qui hai riferimenti per l'acronimo CRALBP
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC124397/


HIH

Luca Gentili
Belgium
Local time: 23:37
Native speaker of: Italian
PRO pts in category: 11
Notes to answerer
Asker: Grazie, purtroppo ero in consegna e ho scelto proteina legante cis retinale.

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