variable/diversity/joining (VDJ) arrangement

Italian translation: ricombinazione VDJ (variabile/diversità/giunzione)

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:variable/diversity/joining (VDJ) arrangement
Italian translation:ricombinazione VDJ (variabile/diversità/giunzione)
Entered by: Francesco D'Arcangeli

08:48 Apr 28, 2019
English to Italian translations [PRO]
Medical - Medical (general) / genetics, neuropathies
English term or phrase: variable/diversity/joining (VDJ) arrangement
This text is about neuropathies but this section focusses on CSF examination and genetic markers.
"If the clinical examination is in keeping with central ner-vous system (CNS) disease, evidence for malignancy should be sought by immunocytology, flow cytometry, molecular studies and immunofixation of the CSF or vitreous fluid. Using polymerase chain reaction analysis of CSF or vitreous fluid, IGH rearrangement studies to amplify the CDR-3 region of the IGH a neoplastic proliferation of lymphocytes, with a unique variable/diversity/joining (VDJ) arrangement will result in a single sharp band on agarose gel. Detection of MYD88 L265P in CSF has been shown to be helpful in the confirmation of CNS involvement by WM (Bing-Neel syndrome). A single large volume (10 ml) CSF sample will have a 50% chance of identifying pathological cells; three serial 10 ml samples increases the pick-up rate to about 90%."
Francesco D'Arcangeli
Italy
Local time: 10:12
ricombinazione VDJ (variabile/diversità/giunzione)
Explanation:
- https://it.wikipedia.org/wiki/Ricombinazione_V(D)J

- http://infermieristica.polodidatticopanico.com/wp-content/up...

- http://biblioteca.asmn.re.it/allegati/mmgsunto24012011_11031...
Selected response from:

Eleonora_P
Italy
Local time: 10:12
Grading comment
Thanks a ton and sorry for the late answer!
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1ricombinazione VDJ (variabile/diversità/giunzione)
Eleonora_P


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
variable/diversity/joining (vdj) arrangement
ricombinazione VDJ (variabile/diversità/giunzione)


Explanation:
- https://it.wikipedia.org/wiki/Ricombinazione_V(D)J

- http://infermieristica.polodidatticopanico.com/wp-content/up...

- http://biblioteca.asmn.re.it/allegati/mmgsunto24012011_11031...

Eleonora_P
Italy
Local time: 10:12
Specializes in field
Native speaker of: Native in ItalianItalian
PRO pts in category: 100
Grading comment
Thanks a ton and sorry for the late answer!

Peer comments on this answer (and responses from the answerer)
agree  Serena Arduini
1 hr
  -> Grazie Serena :)
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