Severe peritubular capillary basement membrane multilayering

09:26 Mar 19, 2020
English to Italian translations [PRO]
Medical - Medical (general) / Nefrologia (rigetto di trapianto)
English term or phrase: Severe peritubular capillary basement membrane multilayering
Uno dei criteri utilizzati nella classificazione di Banff che definiscono la presenza di rigetto cronico attivo mediato da anticorpi
Lucia Zirattu
United Kingdom
Local time: 12:42


Summary of answers provided
4Multilayering acuto della membrana basale capillare peritubulare
Mariana Avram
3Grave formazione di strati della membrana basale intorno ai capillari peritubulari
Luigi Argentino


Discussion entries: 3





  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
Multilayering acuto della membrana basale capillare peritubulare


Explanation:
Ne ho trovato menzione nell'articolo che allego dove viene discussa la classificazione di Banff


    https://ita.webtechwork.com/transplant-glomerulopathy-435894
Mariana Avram
Italy
Local time: 13:42
Native speaker of: Native in MoldavianMoldavian, Native in ItalianItalian
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
severe peritubular capillary basement membrane multilayering
Grave formazione di strati della membrana basale intorno ai capillari peritubulari


Explanation:
Explanation (from the reference below):

"Severe peritubular capillary basement membrane multilayering (PTCBML) is part of the Banff definition of chronic antibody-mediated rejection. We retrospectively investigated whether assessment of the mean number of layers of basement membrane (BM) around peritubular capillaries (PTC) can be used in a cohort of patients with de novo donor-specific antibodies (dnDSA) as an early marker to predict long-term antibody-mediated injury."

https://www.ncbi.nlm.nih.gov/pubmed/26413993


IMO "grave" is better than "acuto".
Explanation (from the reference below):

"Severe peritubular capillary basement membrane multilayering (PTCML) is one diagnostic feature of cABMR. According to the Banff 2013 classification, severe PTCML is defined as ≥7 layers in one cortical peritubular capillary (PTC) and ≥5 layers in two additional capillaries assessed via electron microscopy (EM) 4"

https://onlinelibrary.wiley.com/doi/full/10.1111/tri.12921



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Note added at 5 hrs (2020-03-19 15:23:15 GMT)
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Or:
"Grave presenza di più strati................."

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Note added at 7 hrs (2020-03-19 16:34:42 GMT)
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Or even better:
" Grave multistratificazione.........."

Luigi Argentino
Italy
Local time: 13:42
Specializes in field
Native speaker of: Italian
PRO pts in category: 237
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