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plasma through concentration

Latvian translation: minimālā koncentrācija plazmā (Cmin)

06:50 May 4, 2009
English to Latvian translations [PRO]
Medical - Medical (general) / Zāļu apraksts
English term or phrase: plasma through concentration
Extract: the 90% CI relates to the population effects, whereas in clinical practice the substantial intra-individual variability is critical for the variable ciclosporin blood levels and this is the reason why it is monitored by frequent plasma through concentration even with the brand leader
Liene Lielmane
Latvia
Local time: 02:22
Latvian translation:minimālā koncentrācija plazmā (Cmin)
Explanation:

Normāli būtu jālieto: Trough plasma concentration

The plasma level of a pharmaceutical product measured just before the next dose; Cmin; the opposite of maximal concentration (Cmax)

http://www.definition-of.com/trough concentration

Pharmacokinetic (PK) parameters, such as plasma through concentration (Cmin)
Cmax
The maximum (peak) amount of drug measurable in the blood after a dose is administered.

Cmin
The lowest (trough) amount of drug measurable in the blood after a dose is administered.

Mazākā, asins plazmā nosakāmā zāļu koncentrācija pēc devas ievadīšanas un pirms nākamās devas lietošanas

Selected response from:

Inese Poga-Smith
Canada
Local time: 19:22
Grading comment
Paldies
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +1minimālā koncentrācija plazmā (Cmin)
Inese Poga-Smith


  

Answers


6 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
minimālā koncentrācija plazmā (Cmin)


Explanation:

Normāli būtu jālieto: Trough plasma concentration

The plasma level of a pharmaceutical product measured just before the next dose; Cmin; the opposite of maximal concentration (Cmax)

http://www.definition-of.com/trough concentration

Pharmacokinetic (PK) parameters, such as plasma through concentration (Cmin)
Cmax
The maximum (peak) amount of drug measurable in the blood after a dose is administered.

Cmin
The lowest (trough) amount of drug measurable in the blood after a dose is administered.

Mazākā, asins plazmā nosakāmā zāļu koncentrācija pēc devas ievadīšanas un pirms nākamās devas lietošanas




    Reference: http://www.allcountries.org/hiv_aids/glossary_c.html
    Reference: http://www.aegis.com/conferences/hivdrw/2002/150.html
Inese Poga-Smith
Canada
Local time: 19:22
Specializes in field
Native speaker of: Latvian
PRO pts in category: 184
Grading comment
Paldies

Peer comments on this answer (and responses from the answerer)
agree  Doroteja
18 hrs
  -> Paldies!
agree  Inga Baranova
3 days 57 mins
disagree  Dusan Savic: I am sorry to disagree but there seems to be three different concentrations that are measured i.e. Cmin, Cmax and Cthrough the latter actually being the concentration imminently prior to the administration of the next dose. Cmin might be the same as Ctrou
136 days
  -> You should read the full sentence in Latvian which says that and explains what minimum concentration.
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