conformational change

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13:01 Apr 27, 2009

English to Lithuanian translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics

English term or phrase: conformational change

Definition from Biochemical Society:
Large, medium or small adjustment to the molecular shape/dynamics of a protein that may follow a change in environment or the specific recognition of another molecule.

Example sentence(s):

These observations indicate that heparin, in addition to causing aggregation, also induces a conformational change in tau in which reactive groups are unmasked or move closer leading to the DSS cross-linking of 72- and 83-kDa species. jbc online
At low pH, the hemagglutinin (HA) of influenza virus undergoes an irreversible conformational change that potentiates its essential membrane fusion function. The Rockefeller University Press
To develop the antibody chip for detecting the Bax conformational change, we immobilized Bax monoclonal antibody 6A7, which recognizes only a conformationally changed Bax protein on a gold surface. Elsevier Inc.

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Summary of translations provided

4 +1

konformacijos pokyčiai

Rasa Zurbaite

Discussion entries: 1

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konformacijos pokyčiai

Definition from Aiškinamasis tekstilės terminų žodyn:
Konformacinis virsmas (conformational transformation) - polimero makromolekulių vidutinių konformacijų pakitimas iš rangytesnių į tiesesnes arba atvirkščiai

Konformacija - molekulės momentinis erdvinis pavidalas, priklausantis nuo atomų ar grupių sukimosi apie juos jungiančius cheminius ryšius. (http://www.chemija.ctf.ktu.lt/organikai/spauda/Poligrafkli.p...

Example sentence(s):

Hormono-receptoriaus kompleksas. Prie receptoriaus aktyviojo centro prisijungia hormonas=>konformaciniai pokyčiai=>signalo perdavimas ląstelei. - www.mokslai.lt
Teigiamas kooperatyvinis efektas pasiekiamas dėl hemoglobino konformacinių pokyčių: vienam hemoglobino molekulės subvienetui prisijungus O2 molekulę, pasikeičia tetramero molekulės fragmentų išsidėstymas erdvėje taip, kad palengvėja likusių 3 O2 molekulių prijungimas. - vikipedia
Dėl konformacijos pokyčio baltymai įgauna arba praranda tam tikrą aktyvumą („įjungiami“ arba „išjungiami“). - gamta.vdu.lt

Explanation:
"konformaciniai pokyčiai" arba "konformacijos kitimai"

Rasa Zurbaite
Native speaker of:

Lithuanian

Notes to answerer

Lina Karbauskaite (X) Manau, kad tinkamesnis variantas konformacijos pokyčiai.

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