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vitamin k-dependent plasma glycoprotein

Polish translation: glikoproteina osocza zależna od witaminy K

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00:55 May 17, 2020
English to Polish translations [PRO]
COVID-19 - Science - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: vitamin k-dependent plasma glycoprotein
Definition from Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z

Example sentence(s):
  • This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. National Center for Biotechnology Info.
  • Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. Research Gate
  • Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. The JBC
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


This question is closed

Polish translation:glikoproteina osocza zależna od witaminy K
Definition:
Do białek zależnych od witaminy K zalicza się osteokalcynę, białka C, S, Z oraz czynniki krzepnięcia krwi: II, VII, IX, X.
Selected response from:

Robert Foltyn
Poland
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
3 +2glikoproteina osocza zależna od witaminy K
Robert Foltyn


  

Translations offered


11 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
glikoproteina osocza zależna od witaminy K


Definition from ANNALES ACADEMIAE MEDICAE SILESIENSIS:
Do białek zależnych od witaminy K zalicza się osteokalcynę, białka C, S, Z oraz czynniki krzepnięcia krwi: II, VII, IX, X.

Example sentence(s):
  • Białko S jest glikoproteiną zależną od witaminy K. Syntetyzowane jest w wątrobie oraz przez komórki śródbłonka, megakariocyty i komórki Leydiga jąder. W osoczu występuje w 2 formach: wolnej i związanej z białkiem układu dopełniacza. - Medica, Radom  
  • Białko C (protein C, PC) i białko S (protein S, PS) to zależne od witaminy K glikoproteiny będące naturalnymi inhibitorami krzepnięcia krwi. - Uniwersytet Medyczny, Wrocław  
  • Białko C  Zależna od witaminy K glikoproteina osocza  Synteza zachodzi w wątrobie  Występuje w głównie w formie nieaktywnej (85-90%)  Aktywacja następuje na powierzchni komórek śródbłonka naczyń przez kompleks trombina-trombomodulina - Klinika Neonatologii ICZMP w Łodzi  
Robert Foltyn
Poland
Local time: 07:38
Native speaker of: Native in PolishPolish
PRO pts in category: 467

Votes in favor of/against selecting this as the best translation of the term asked
Yes  KORNELIA ZWIÓR-HOŁENKO: dobrze udokumentowane
5 hrs
Yes  Frank Szmulowicz, Ph. D.
3 days 21 mins
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