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Novel hormonal therapy (NHT)

Portuguese translation: Nova terapia hormonal

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Novel hormonal therapy (NHT)
Portuguese translation:Nova terapia hormonal

21:37 Mar 24, 2020
    The asker opted for community grading. The question was closed on 2020-03-28 16:54:08 based on peer agreement (or, if there were too few peer comments, asker preference.)


English to Portuguese translations [PRO]
Medical - Medical: Pharmaceuticals / oncology
English term or phrase: Novel hormonal therapy (NHT)
**Novel hormonal therapy** for the treatment of benign metastasizing leiomyoma: an analysis of 5 cases and literature review

Abstract
Objective
To evaluate **novel hormonal therapies** in patients with unresectable Benign Metastasizing Leiomyoma (BML) disease.

Design
Case series.

Setting
National Institutes of Health (NIH).

Patients
5 subjects with the diagnosis of BML based on imaging and/or histopathologic diagnosis.

Interventions
Four patients were treated with single or combination therapy of Leuprolide acetate and/or an aromatase inhibitor. One patient was treated with an antiprogestin (CDB-2914).
Fernando Petracioli
Brazil
Local time: 16:28
Nova terapia hormonal
Explanation:
Sugestão.
Selected response from:

Augusto Rochadel
Brazil
Local time: 16:28
Grading comment
Selected automatically based on peer agreement.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +4Nova terapia hormonal
Augusto Rochadel
5 +1terapêutica hormonal inovadora
Madalena Ribeiro
4 +1terapia hormonal neoadjuvante (nht - novel hormonal therapy)
Clauwolf
3hormonoterapia/terapia hormonal com novos agentes
expressisverbis


  

Answers


4 mins   confidence: Answerer confidence 5/5 peer agreement (net): +1
novel hormonal therapy (nht)
terapêutica hormonal inovadora


Explanation:
terapêutica hormonal inovadora

Madalena Ribeiro
Local time: 20:28
Specializes in field
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 40

Peer comments on this answer (and responses from the answerer)
agree  Maria Teresa Borges de Almeida
10 hrs
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9 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +4
novel hormonal therapy (nht)
Nova terapia hormonal


Explanation:
Sugestão.

Augusto Rochadel
Brazil
Local time: 16:28
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 20
Grading comment
Selected automatically based on peer agreement.

Peer comments on this answer (and responses from the answerer)
agree  Katarina Peters
18 mins
  -> Obrigado
agree  Paulinho Fonseca
2 hrs
  -> Obrigado
agree  Tereza Rae
2 hrs
  -> Obrigado
agree  Kathleen Goldsmith-Killing
15 hrs
  -> Obrigado
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29 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
novel hormonal therapy (nht)
hormonoterapia/terapia hormonal com novos agentes


Explanation:
Novel agents in the management of castration resistant prostate cancer

Eventually however all men will progress to castration-resistant prostate cancer (CRPC). Insight into the molecular mechanisms of androgen resistance has led to the development of alternative novel hormonal agents.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007389/

Esta dissertação pretende ser uma revisão bibliográfica sobre o tratamento hormonal do cancro da próstata metastizado, fazendo uma breve introdução a este cancro tão prevalente e abordando as
principais opções de tratamento atualmente disponíveis dando especial relevo à temática do cancro da próstata resistente à castração hormonal e aos novos agentes e alvos moleculares com potencial para alterar a sobrevida geral e a qualidade de vida destes doentes.
https://webcache.googleusercontent.com/search?q=cache:XWxU8W...

Neste vídeo, o Dr Karim Fizazi questiona a utilidade do uso de agentes hormonais “antigos” antes do uso de drogas de segunda geração para o tratamento do CPRC metastático e não metastático. Esses agentes antigos possuem fraca atividade nesse cenário.
https://www.oncologiabrasil.com.br/produto/conceitos-basicos...

A hormônioterapia, por sua vez, baseia-se na utilização de agentes como o tamoxifeno, que apresenta efeito antagônico ao estrogênio.
https://www.conhecer.org.br/enciclop/2017b/agrar/quimioterap...

https://www.infopedia.pt/dicionarios/lingua-portuguesa/hormo...

Não encontrei nada como terapia hormonal nova ou inovadora.
Do que li, penso que "novel" se refere a "novos" agentes utilizados em tratamentos como radioterapia, hormonoterapia, ou quimioterapia, por oposição a agentes "antigos".

--------------------------------------------------
Note added at 39 mins (2020-03-24 22:16:37 GMT)
--------------------------------------------------

A hormonioterapia é mais comumente utilizada para tratar o câncer metástico, isto é, que tenha se disseminado para fora da próstata (Estágios N+ e M+).
Os análogos do LHRH atualmente disponíveis são o ZOLADEX® (Acetato de gosserrelina para implante), Lupron Depot® (acetato de leuprolida para suspensão de depósito), e Viadur™ (acetato de leuprolida para implante).
https://www.portalsaofrancisco.com.br/saude/hormonioterapia

Agentes como leuprolide e goserelina são medicamentos cujo uso contínuo inibe a secreção pulsátil do GnRH, o que culmina com a supressão dos níveis de testosterona. Além disso, foi disponibilizado mais recentemente o degarelix.
https://www.minhavida.com.br/saude/materias/18262-cancer-de-...

expressisverbis
Portugal
Local time: 20:28
Specializes in field
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 140
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20 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
novel hormonal therapy (nht)
terapia hormonal neoadjuvante (nht - novel hormonal therapy)


Explanation:
:) https://mocbrasil.com/blog/noticias/nova-opcao-de-tratamento...

Clauwolf
Local time: 16:28
Works in field
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 218

Peer comments on this answer (and responses from the answerer)
agree  Marilia Sette Câmara: https://docplayer.com.br/77430720-European-association-of-ur... http://www.hcancerbarretos.com.br/upload/doc/79b8371ced62ede... https:
551 days
  -> obrigado
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