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  3. Biology (-tech,-chem,micro-)

the tumor-targeting saturation binding abundance

Russian translation: см.

17:14 Nov 4, 2019
English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-) / иммунология�
English term or phrase: the tumor-targeting saturation binding abundance
The present disclosure provides a bispecific recombinant protein and a use thereof, which can significantly enhance ***the tumor-targeting saturation binding abundance*** of a recombinant protein with an effect of modulating the function of macrophages and reduce non-tumor-target side effects.
The bispecific recombinant protein described herein can significantly enhance ***the tumor-targeting saturation binding abundance*** of a recombinant protein with an effect of modulating the function of macrophages and reduce non-tumor target side effects, as long as the ratio of the binding affinity of the antibody corresponding to the ‘high affinity tumor-targeting arm’ to the target antigen on tumor cell to the binding affinity of the homodimer of the monomer fusion protein corresponding to the ‘fusion protein with low affinity for blocking the interaction between CD47 and SIRPα to CD47’on tumor cell is at least 6.
Nitrogen
Local time: 23:41
Russian translation:см.
Explanation:
enhance the tumor-targeting saturation binding abundance of a recombinant protein ~ увеличивает [относительное] содержание рекомбинантного белка, обеспечивающего его насыщающее/конкурентное(?) связывание с опухолевыми мишенями


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Note added at 3 hrs (2019-11-04 21:08:17 GMT)
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содержание рекомбинантного белка, обеспечивающЕЕ...
Selected response from:

Igor Andreev
Local time: 23:41
Grading comment
Большое спасибо
4 KudoZ points were awarded for this answer



Summary of answers provided
3см.
Igor Andreev


  

Answers


3 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
см.


Explanation:
enhance the tumor-targeting saturation binding abundance of a recombinant protein ~ увеличивает [относительное] содержание рекомбинантного белка, обеспечивающего его насыщающее/конкурентное(?) связывание с опухолевыми мишенями


--------------------------------------------------
Note added at 3 hrs (2019-11-04 21:08:17 GMT)
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содержание рекомбинантного белка, обеспечивающЕЕ...

Igor Andreev
Local time: 23:41
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1427
Grading comment
Большое спасибо
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