glycan occupancy

Russian translation: занятость участков связывания [гликана]

15:00 Nov 20, 2019
English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-) / иммунология�
English term or phrase: glycan occupancy
All three of these variants had the common mutated sites K75N/C77T. cIEF data showed that the K75N/C77T/K82T variant had a clear acidic shift of pI compared to a K82T variant (Figure 5B), which indicated the potential occupation of a negatively charged glycan moiety at the K75N site that caused both the MW and pI shift. To further confirm the status of ***the glycan occupation*** on all introduced N-linked glycosylation sites, LC/MS-based characterization was performed.

The three variants which contained the same K75N/C77T mutations had variable ***glycan occupancy*** with similar mole sialic acid per mole oligosaccharide ratios on N75. The degree of mobility shift on polyacrylamide electrophoresis gel was consistent with the degree of ***glycan occupancy*** on N75 for three hyperglycosylated variants. Wild type, ΔHBS variant, and all 10 designed glycan variants had similar glycan occupancy and sialic acid content on native FS glycan sites N112 and N259, but quite variable occupancy on N95.
Nitrogen
Local time: 07:56
Russian translation:занятость участков связывания [гликана]
Explanation:
Так и будет, буквально.

Например:

To further confirm the status of the glycan occupation on all introduced N-linked glycosylation sites = Чтобы далее подтвердить статус занятости всех введенных N- связанных участков гликозилирования, ...

Вот в уже переведенном патенте встречается:
EA 012802B1 20091230
предпочтительно 3 занятых N-связанных сайта гликозилирования, а также ....
www.eapatis.com › scripts › ShowEAPO

Только не пишите "сайты"!
Selected response from:

Natalie
Poland
Local time: 06:56
Grading comment
Спасибо!

4 KudoZ points were awarded for this answer



Summary of answers provided
5 +1занятость участков связывания [гликана]
Natalie
3степень гликозилирования
Pavel Altukhov


  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
степень гликозилирования


Explanation:
http


    Reference: http://https://ru.wikipedia.org/wiki/%D0%93%D0%BB%D0%B8%D0%B...
Pavel Altukhov
Local time: 07:56
Works in field
Native speaker of: Russian
PRO pts in category: 28
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18 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
занятость участков связывания [гликана]


Explanation:
Так и будет, буквально.

Например:

To further confirm the status of the glycan occupation on all introduced N-linked glycosylation sites = Чтобы далее подтвердить статус занятости всех введенных N- связанных участков гликозилирования, ...

Вот в уже переведенном патенте встречается:
EA 012802B1 20091230
предпочтительно 3 занятых N-связанных сайта гликозилирования, а также ....
www.eapatis.com › scripts › ShowEAPO

Только не пишите "сайты"!

Natalie
Poland
Local time: 06:56
Specializes in field
Native speaker of: Russian
PRO pts in category: 4329
Grading comment
Спасибо!

Peer comments on this answer (and responses from the answerer)
agree  Igor Andreev: Да, простите, не вчитался внимательно. Речь не о гликозилировании, а о связывании с гликанами
3 hrs
  -> Спасибо! Чтобы было понятнее - не "гликана", а "гликановых". Ничем не лучше, просто как-то принято так писать о занятости участков связывания.
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