fluorescent probe exclusion assays

Russian translation: здесь: результаты экспериментов по исключению флуоресцентной метки

09:06 Nov 25, 2019
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: fluorescent probe exclusion assays
Stabilization values averaged between Western blot and fluorescent probe exclusion assays (except Diflunisal, which includes only Western blot); tafamidis either purchased commercially or synthesized for research use
NIS=Neuropathic Impairment Score; NIS-LL=NIS of Lower Limbs; NIS+7=NIS plus 7 nerve tests; mNIS+7=modified NIS plus 7 nerve tests
Maxim Polukhin
Local time: 17:29
Russian translation:здесь: результаты экспериментов по исключению флуоресцентной метки
Explanation:
Эксперименты, позволяющие определить занятость участков связывания.
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Natalie
Poland
Local time: 15:29
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Summary of answers provided
4здесь: результаты экспериментов по исключению флуоресцентной метки
Natalie
4тест с ингибированием связывания флуоресцентной метки
Igor Andreev


  

Answers


36 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
здесь: результаты экспериментов по исключению флуоресцентной метки


Explanation:
Эксперименты, позволяющие определить занятость участков связывания.

Natalie
Poland
Local time: 15:29
Specializes in field
Native speaker of: Russian
PRO pts in category: 13399
Grading comment
Спасибо!
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6 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
тест с ингибированием связывания флуоресцентной метки


Explanation:
я бы все же назвал это так
см. описание метода:
FPE assay for binding TTR in buffer and human or dog serum.

The binding affinity and selectivity of AG10 and other stabilizers to TTR in buffer and serum was determined by their ability to compete with the binding of a fluorescent probe exclusion (FPE probe) binding to TTR in buffer and human serum.18 The FPE probe is a thioester TTR ligand (Supplementary Figure 1) that is not fluorescent by itself, however upon binding to the T4 binding site of TTR it covalently modifies lysine 15 (K15), creating a fluorescent conjugate.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276790/

Igor Andreev
Local time: 16:29
Native speaker of: Native in RussianRussian
PRO pts in category: 625
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