This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
  1. KudoZ™ Top
  2. English to Russian
  3. Medical: Pharmaceuticals

to change in monomer purity

Russian translation: влиять на мономерную чистоту (сохранение содержание мономера)

10:47 Apr 23, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: to change in monomer purity
In summary, in the antibody formulation provided by the invention, by selecting an appropriate buffer system, optimizing a stabilizer and adding a surfactant, the increase of acidic peaks, aggregates, degradants and insoluble particles in a freezing/thawing cycle, long-term storage and temperature and light change process can be effectively inhibited, and the active ingredients can be stably stored for a long time.
Wherein the selection of buffer system plays the most important role for the stabilization of formulation, and compared with phosphate buffer, histidine salt buffer can significantly inhibit the formation of acidic isomers, aggregates and degradants in long-term storage and temperature change process.
The tendency of the various formulas **to change in monomer purity** (SEC-HPLC, abbreviated SEC) and charge isomer (IEC-HPLC, abbreviated IEC) at a high temperature 40 °C for 21 days was investigated, see Table 2.
The trends of changes in monomer purity (SEC-HPLC, abbreviated as SEC) and charge isomers (IEC-HPLC, abbreviated as IEC) of the various formulas were investigated under the conditions of 25 °C, 40 °C, 50 °C and light for 3 months, as shown in Table 4.
Maxim Polukhin
Local time: 17:01
Russian translation:влиять на мономерную чистоту (сохранение содержание мономера)
Explanation:
Настоящее жаргонное научное выражение
Изучают составы лекпрепарата на способность сохранять действующее вещество (антитело в виде мономера) неизменным
Может опечатка от "charge"
Selected response from:

Oleksandr Mandzhos
Ukraine
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4влиять на мономерную чистоту (сохранение содержание мономера)
Oleksandr Mandzhos


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
влиять на мономерную чистоту (сохранение содержание мономера)


Explanation:
Настоящее жаргонное научное выражение
Изучают составы лекпрепарата на способность сохранять действующее вещество (антитело в виде мономера) неизменным
Может опечатка от "charge"

Oleksandr Mandzhos
Ukraine
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 70
Grading comment
Спасибо!
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Return to KudoZ list

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.

See also:
ProZ.com term search
Search millions of term translations
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search