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good buffer protection role

Russian translation: выступает в качестве благоприятной буферной защиты

11:17 Apr 23, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: good buffer protection role
After high temperature experiments, either SEC aggregation or IEC acidic peaks were significantly lower than those of other buffers or combination buffers.
To select histidine salt concentration, histidine salt buffer was prepared at concentrations ranging from 5-20mM, with protein concentration of 20mg/ml, pH 6.0-6.4.
The trends of SEC and IEC after 21 days of exposure to 40 °C high temperature were investigated, see Table 3.
It can be seen that histidine buffer could play a good buffer protection role in the range of 5-20mM.
To select the optimal pH of the formulation buffer, histidine salt buffer was prepared at a concentration of 10mM with a protein concentration of 20mg/ml in the pH range 5.4-6.9.
The trends of SEC and IEC after 21 days of exposure to 40 °C high temperature were investigated, see Figure 1.
As can be seen from the mapping of the main peak data of SEC-HPLC and IEC tests, the pH in the range of 5.7-6.2 could play a **good buffer protection role** as time went by. pH 6.2 is better than pH 6.0 and better than other pH.
The results showed that the sample had a higher stability at pH 6.2.
Table 2.
Formulation Buffer Selection at High Temperature (40 °C)
Maxim Polukhin
Local time: 07:48
Russian translation:выступает в качестве благоприятной буферной защиты
Explanation:
кому больше нравятся театральные представления, можно и "играть роль"
Selected response from:

Oleksandr Mandzhos
Ukraine
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4выступает в качестве благоприятной буферной защиты
Oleksandr Mandzhos


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
выступает в качестве благоприятной буферной защиты


Explanation:
кому больше нравятся театральные представления, можно и "играть роль"

Oleksandr Mandzhos
Ukraine
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 70
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Спасибо!
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