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  3. Medical: Pharmaceuticals

content of IEC-HPLC main peaks

Russian translation: главные пики при ионообменной ВЭЖХ

13:13 Apr 23, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: content of IEC-HPLC main peaks
The main peak was the chromatographic peak of the whole antibody protein, the impurity peak before the main peak was the chromatographic peak of Fraction (including L peak, H peak, HL, HH and HHL peaks), and the percentage content of the monomer peak was calculated by an area normalization method.
It can be seen from Table 9 that under the acceleration conditions, the monomer purity decreased with time over 6 months, indicating that aggregates were produced under the acceleration conditions, but the SEC main peak of the antibody decreased by no more than 2.28%; with respect to IEC-HPLC, under the condition of 25 °C, the **content of IEC-HPLC main peaks** of antibody decreased, and the degradation trend was basically the same, and the IEC main peak decreased by no more than 16.54%; the CE-SDS-NR main peak decreased by no more than 2.1%, insoluble particles were far lower than qualified standards, cell active substances did not change obviously, which indicates that the antibody formulations can still maintain stability within 6 months at room temperature.
Maxim Polukhin
Local time: 01:45
Russian translation:главные пики при ионообменной ВЭЖХ
Explanation:
Под "сontent" здесь понимается величина пика:
Selected response from:

Natalie
Poland
Local time: 00:45
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4главные пики при ионообменной ВЭЖХ
Natalie


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
content of iec-hplc main peaks
главные пики при ионообменной ВЭЖХ


Explanation:
Под "сontent" здесь понимается величина пика:

Natalie
Poland
Local time: 00:45
Specializes in field
Native speaker of: Russian
PRO pts in category: 13399
Grading comment
Спасибо!
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