dose-dense fashion

Russian translation: дозоуплотненный режим [химиотерапии]

08:45 Oct 21, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: dose-dense fashion
With regards to the chemotherapy regimen following anthracyclines, a randomized controlled trial conducted by the Eastern Cooperative Oncology Group (ECOG) (N Engl J Med. 2008;358(16):1663) demonstrated that paclitaxel is more effective when used in a lower, dose-dense fashion.

The patient’s treating physician stated a chemotherapy programme comprising 4 cycles of dose-dense Doxorubicin dosed at 100mg/m2 and Cyclophosphamide dosed at 1000mg/m2 every 14 days.
Maxim Polukhin
Local time: 22:28
Russian translation:дозоуплотненный режим [химиотерапии]
Explanation:
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Selected response from:

Natalie
Poland
Local time: 21:28
Grading comment
Спасибо!
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Summary of answers provided
4 +1дозоуплотненный режим [химиотерапии]
Natalie
4применение сниженных доз с большей частотой
Margarita Vidkovskaia


  

Answers


51 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
дозоуплотненный режим [химиотерапии]


Explanation:
*

Natalie
Poland
Local time: 21:28
Specializes in field
Native speaker of: Russian
PRO pts in category: 13399
Grading comment
Спасибо!

Peer comments on this answer (and responses from the answerer)
agree  svetlana cosquéric
2 hrs
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53 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
применение сниженных доз с большей частотой


Explanation:
..эффективность терапии паклитакселом выше при применении сниженных доз с большей частотой [по сравнению со стандартным режимом химиотерапии].

A chemotherapy treatment plan in which drugs are given with less time between treatments than in a standard chemotherapy treatment plan.
https://www.cancer.gov/publications/dictionaries/cancer-term...

By decreasing the dose and increasing the frequency, the fast growth can be prevented, allowing for faster and more effective cure rate. Although the dose is reduced in each treatment, the total quantity of chemotherapy may or may not be increased over the duration of the typical treatment time.

Margarita Vidkovskaia
Russian Federation
Local time: 22:28
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 964
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