exposure distribution
Serbian translation: distribucija izloženosti (pacijenta leku)
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| 23:20 Dec 18, 2019 |
| English to Serbian translations [Non-PRO] Medical - Medical: Pharmaceuticals / pharmacokinetics | |||||
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|  Selected response from: Dragana Samardžijević Local time: 12:15 | ||||
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| 4 | distribucija izloženosti (pacijenta leku) |
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Answers
1 day 13 hrs confidence: 
distribucija izloženosti (pacijenta leku) Explanation: Objašnjenje pojma "distribucija" u okviru oblasti farmakokinetike. "Pharmacokinetics Distribution – the dispersion or dissemination of substances throughout the fluids and tissues of the body." https://en.wikipedia.org/wiki/Pharmacokinetics Primer iz domaćeg izvora u istom kontekstu... "Eliglustat se umereno veže za ljudske proteine plazme (76% do 83%) i uglavnom se distribuira u plazmi. Nakon intravenske primene, volumen distribucije bio je 816 L, što upućuje na široku distribuciju u tkiva kod ljudi." https://www.alims.gov.rs/ciril/files/lekovi/smpc/515-01-0333... Primeri upotrebe pojma "izloženost" iz domaćih izvora, isto iz oblasti farmakokinetike. Obim izloženosti pacijenata leku (Patient exposure) – procenjeni broj. https://pks.rs/SADRZAJ/Files/Udruženje za farmaceutsku i med... https://www.nuventra.com/services/pharmacokinetics-pharmacod... Upotreba leka Cabometyx se ne preporučuje kod pacijenata sa teškim oštećenjem funkcije jetre (Child-Pugh C) budući da kabozantinib nije ispitan kod te populacije i izloženost može biti povećana kod tih pacijenata. https://www.alims.gov.rs/wp-content/blogs.dir/2/files/lekovi... |
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