XPG cleaves 3’

Spanish translation: XPG corta en 3’ / en el extremo 3'

01:00 Apr 4, 2021
English to Spanish translations [PRO]
Medical - Medical (general) / XPG cleaves 3’
English term or phrase: XPG cleaves 3’
Buenos días,

Espero que puedan ayudarme con una expresión al español: “XPG cleaves 3’”, relacionada con un anticuerpo para inmunotinción. Muchas gracias.

“This antibody reacts with a protein known as ERCC1 (excision repair cross complementing) polypeptide. ERCC1 is required for nucleotide excision repair of damaged DNA and is homologous to RAD10. In mammalian cells, XPG cleaves 3’ f the DNA lesion while ERCC1‐XPF complex makes the 5’ incision.”

GVL
Giovanni Castaneda
Peru
Local time: 10:04
Spanish translation:XPG corta en 3’ / en el extremo 3'
Explanation:
En https://en.wikipedia.org/wiki/XPG_I_protein_domain
"XPG cleaves the 5'-overhanging flap structure that is generated when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment."

Allí "cleaves" tiene un enlace a la explicación de esta acción, a:
https://en.wikipedia.org/wiki/Bond_cleavage

"Bond cleavage, or bond fission, is the splitting of chemical bonds. This can be generally referred to as dissociation when a molecule is cleaved into two or more fragments.[1]"

Significado de "to cleave":
cleave verb (2)
Definition of cleave (Entry 2 of 2)
transitive verb
1 : to divide by or as if by a cutting blow : split The blow cleaved the victim's skull.
2 : to separate into distinct parts and especially into groups having divergent views The political party was cleaved by internal bickering.
3 : to subject to chemical cleavage a protein cleaved by an enzyme
https://www.merriam-webster.com/dictionary/cleave

En español (incluso para la acción de enzimas) se utilizan los términos ruptura o disociación de enlace químico

Ejemplo: https://es.wikipedia.org/wiki/Homólisis
https://es.wikipedia.org/wiki/Heterólisis
https://es.wikipedia.org/wiki/Energía_de_disociación_de_enla...

En https://www.google.com/search?q="xpg rompe"
veo que hay muy escasas citas con "XPG rompe la cadena ..." o "XPG rompe los segmentos..."

https://www.google.com/search?q="xpg corta"
muestra MUCHOS usos de la expresión "XPG corta la cadena..." o la hebra

Uso con 3':

"XPG: corta en 3' liberándolo."
https://coggle.it/diagram/XOfHKYqK7gbfo6UP/t/reparación-dna

XPG corta el. DNA en 3'
http://depa.fquim.unam.mx/amyd/archivero/UNIDAD_5_DEFECTOS_R...

XPG corta la hebra en el extremo 3' de la lesión
https://www.academia.edu/23111579/REPARACIÓN_DEL_ADN?auto=do...

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Note added at 42 mins (2021-04-04 01:43:24 GMT)
--------------------------------------------------

"XPG corta" es encontrado 283 veces en Google Search.
"XPG escinde" es encontrado sólo 2 veces. Prácticamente no se utiliza.
Selected response from:

Daniel Delgado
Argentina
Local time: 12:04
Grading comment
Muchas gracias, Daniel.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +3XPG corta en 3’ / en el extremo 3'
Daniel Delgado
4la (endonucleasa) XPG escinde el extremo 3'
Coralia Maskavizan


Discussion entries: 1





  

Answers


16 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
xpg cleaves 3’
la (endonucleasa) XPG escinde el extremo 3'


Explanation:
También se dice que "corta en (el extremo) 3'", aunque creo que "escisión" es el término adecuado en este contexto.


    https://pdfcoffee.com/genes-ix-espaolocr-5-pdf-free.html
    https://filadd.com/doc/replicacin-mantenimiento-y-reorganizacion-del-4
Coralia Maskavizan
Argentina
Local time: 12:04
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 16
Login to enter a peer comment (or grade)

37 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
XPG corta en 3’ / en el extremo 3'


Explanation:
En https://en.wikipedia.org/wiki/XPG_I_protein_domain
"XPG cleaves the 5'-overhanging flap structure that is generated when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment."

Allí "cleaves" tiene un enlace a la explicación de esta acción, a:
https://en.wikipedia.org/wiki/Bond_cleavage

"Bond cleavage, or bond fission, is the splitting of chemical bonds. This can be generally referred to as dissociation when a molecule is cleaved into two or more fragments.[1]"

Significado de "to cleave":
cleave verb (2)
Definition of cleave (Entry 2 of 2)
transitive verb
1 : to divide by or as if by a cutting blow : split The blow cleaved the victim's skull.
2 : to separate into distinct parts and especially into groups having divergent views The political party was cleaved by internal bickering.
3 : to subject to chemical cleavage a protein cleaved by an enzyme
https://www.merriam-webster.com/dictionary/cleave

En español (incluso para la acción de enzimas) se utilizan los términos ruptura o disociación de enlace químico

Ejemplo: https://es.wikipedia.org/wiki/Homólisis
https://es.wikipedia.org/wiki/Heterólisis
https://es.wikipedia.org/wiki/Energía_de_disociación_de_enla...

En https://www.google.com/search?q="xpg rompe"
veo que hay muy escasas citas con "XPG rompe la cadena ..." o "XPG rompe los segmentos..."

https://www.google.com/search?q="xpg corta"
muestra MUCHOS usos de la expresión "XPG corta la cadena..." o la hebra

Uso con 3':

"XPG: corta en 3' liberándolo."
https://coggle.it/diagram/XOfHKYqK7gbfo6UP/t/reparación-dna

XPG corta el. DNA en 3'
http://depa.fquim.unam.mx/amyd/archivero/UNIDAD_5_DEFECTOS_R...

XPG corta la hebra en el extremo 3' de la lesión
https://www.academia.edu/23111579/REPARACIÓN_DEL_ADN?auto=do...

--------------------------------------------------
Note added at 42 mins (2021-04-04 01:43:24 GMT)
--------------------------------------------------

"XPG corta" es encontrado 283 veces en Google Search.
"XPG escinde" es encontrado sólo 2 veces. Prácticamente no se utiliza.

Daniel Delgado
Argentina
Local time: 12:04
Native speaker of: Spanish
PRO pts in category: 182
Grading comment
Muchas gracias, Daniel.

Peer comments on this answer (and responses from the answerer)
agree  Z-Translations Translator
17 hrs

agree  Edier Quintana
17 hrs

agree  Leda Roche
19 hrs
Login to enter a peer comment (or grade)



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