wild-type and variant transthyretin tetramers

Spanish translation: tetrámeros de transtiretina naturales [de tipo salvaje] y mutados [variantes, polimorfismos]

20:16 Jul 14, 2019
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / The cardiovascular system
English term or phrase: wild-type and variant transthyretin tetramers
Context:

Data from clinical and ex-vivo studies in the clinical program for tafamidis demonstrated that it stabilizes both wild-type and variant transthyretin tetramers.

Gracias
Maria Iglesia Ramos
Spain
Spanish translation:tetrámeros de transtiretina naturales [de tipo salvaje] y mutados [variantes, polimorfismos]
Explanation:
Wild-type alude a tetrámeros naturales mientra que variant tetramers hace referencia a las mutaciones, polimorfismos o simplemente "variantes" de los naturales -que resultan relevantes en este caso.

El depósito e infiltración del miocardio ocurre cuando la tipo salvaje (wild-type) o variantes TTR se tornan inestables por una conformación y plegado anómalos.

https://secardiologia.es/blog/9830-tafamidis-una-nueva-terap...
Selected response from:

Chema Nieto Castañón
Spain
Local time: 03:23
Grading comment
gracias
4 KudoZ points were awarded for this answer



Summary of answers provided
3tetrámeros de transtiretina naturales [de tipo salvaje] y mutados [variantes, polimorfismos]
Chema Nieto Castañón


  

Answers


15 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
tetrámeros de transtiretina naturales [de tipo salvaje] y mutados [variantes, polimorfismos]


Explanation:
Wild-type alude a tetrámeros naturales mientra que variant tetramers hace referencia a las mutaciones, polimorfismos o simplemente "variantes" de los naturales -que resultan relevantes en este caso.

El depósito e infiltración del miocardio ocurre cuando la tipo salvaje (wild-type) o variantes TTR se tornan inestables por una conformación y plegado anómalos.

https://secardiologia.es/blog/9830-tafamidis-una-nueva-terap...

Chema Nieto Castañón
Spain
Local time: 03:23
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 553
Grading comment
gracias
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