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downstream processing

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00:54 Sep 23, 2020
English to Turkish translations [PRO]
Science - Medical: Pharmaceuticals
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Medical (general)
English term or phrase: downstream processing
Definition from Pharma IQ:
Downstream Processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and human growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering.

Example sentence(s):
  • Downstream processing can also impact the distribution and levels of product-related impurities. Accurate monitoring of product-related impurities, including higher molecular weight and lower molecular weight species is critical for product safety. Science Direct
  • EasyMax chemical reactor is for fundamental parameter optimization in downstream processing method design and execution. METTLER TOLEDO
  • Furthermore, because chromatography can represent a significant portion of the cost of goods in downstream processing (DSP) operations, proper optimization of capacity and selectivity is required. BioPharm
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
4Alt akım işlemleri
Amir Akbarpour Reihani


  

Translations offered


6 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
Alt akım işlemleri


Definition from ResearchGate:
Alt akım işlemleri, biyoteknolojik yollarla üretilmiş ürünlerin amaçlanan kullanıma uygun hale gelmesi için yapılan ayırma ve saflaştırma işlemleridir. Çoğu biyoproses sonunda ürün bir çözelti içinde son derece seyreltik halde bulunur.

Example sentence(s):
  • Mikrobiyal yolla üretilen laktik asitin fermentasyon ortamından kısa sürede, yüksek verimle ve ekonomik olarak ayrılması ve özellikle biyomalzeme alanında kullanılması için, yüksek saflıkta eldesi gerekmektedir. Ancak, laktik asitin maliyetinin büyük kısmını üretiminden çok saflaştırma sırasındaki alt akım işlemleri oluşturmaktadır. Çeşitli alt akım işlemlerinden iyon değiştirme kromatografisinin seçiciliği yüksek olup, düşük maliyetle ürün eldesi için uygun bir prosestir. - IYTE  
  • Melanin pigmentinin oluşumu ve ayrılması için gerekli alt akım işlemleri, mikroorganizma suşunun geliştirilmesiyle elimine edilebilmektedir. - Ulusal Tez Merkezi  
  • Alt akım işlemleri ve biyoteknoloji başlığı altında enzimler ve antibodyler gibi biyoteknolojik ürünlerin saflaştırılması amacıyla laboratuvar ve pilot ölçekte kullanılacak deriştirme, ultrafiltrasyon, kromatografi v.b. unit proseslerin çalışma koşullarının belirlenmesi, optimizasyonu ve tasarlanması çalışmaları gerçekleştirilmektedir. - un-en.net  
Amir Akbarpour Reihani
Local time: 14:02
Native speaker of: Native in Persian (Farsi)Persian (Farsi)
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