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patch

English translation: portion

10:27 Jun 1, 2012
English language (monolingual) [PRO]
Science - Genetics / Genetic systems / DNA
English term or phrase: patch
Text about the functioning of clock genes, sirtuines a.o.:

DNA is bound with special proteins and the sirtuin genes make proteins that can either pull off the other special proteins or put them back on. This is a genetic system in which you can control all genes at once *by opening the DNA as a large patch* and closing it down.

I don't understand the part in ** and I already posted this question on E-G, with no result, though. Can anyone help me? Thanks in advance!
ibz
Local time: 14:19
Selected answer:portion
Explanation:
The DNA strand, when inactive, is folded and packed with proteins (i.e. histones). In this situation, the DNA strand is not available for expression of genes (it is "silenced"). Sirtuin regulate detachment of such proteins from a large portion (patch) of DNA, allowing unwinding of the DNA strand and making it available for translation of large groups of genes contained in that patch. .
Selected response from:

teresa neri
Italy
Local time: 14:19
Grading comment
Thank you very much for your help!
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
3portion
teresa neri


  

Answers


21 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
portion


Explanation:
The DNA strand, when inactive, is folded and packed with proteins (i.e. histones). In this situation, the DNA strand is not available for expression of genes (it is "silenced"). Sirtuin regulate detachment of such proteins from a large portion (patch) of DNA, allowing unwinding of the DNA strand and making it available for translation of large groups of genes contained in that patch. .


    Reference: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753453/
teresa neri
Italy
Local time: 14:19
Specializes in field
Native speaker of: Native in ItalianItalian
PRO pts in category: 4
Grading comment
Thank you very much for your help!
Notes to answerer
Asker: Thank you very much for this explanation!

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