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19:01 Mar 5, 2013 |
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English language (monolingual) [PRO] Medical - Medical (general) / Margins negative but close and the closest margin was 2.8 mm | |||||||
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| Selected response from: Marga Shaw United Kingdom Local time: 10:23 | ||||||
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SUMMARY OF ALL EXPLANATIONS PROVIDED | ||||
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4 +1 | Close margins: Any situation that falls between positive and negative is considered "close." |
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Close margins: Any situation that falls between positive and negative is considered "close." Explanation: Margins, also known as "margins of resection," refer to the distance between a tumor and the edge of the surrounding tissue that's removed along with it. ... Positive margins: Cancer cells extend out to the edge of the tissue, where the ink is. Negative margins: No cancer cells are found in the ink. Close margins: Any situation that falls between positive and negative is considered "close." http://www.breastcancer.org/questions/margins http://www.breastcancer.org/symptoms/diagnosis/margins Other observational studies also suggest that for DCIS, a close margin may increase the hazard of local recurrence,[15] and therefore it may be reasonable to define the optimal free margin for DCIS as a width of 2 mm. http://reveszmd.com/breast-cancer-surgeon-san-diego/publicat... DCIS margin index was calculated as closest margin distance of DCIS (mm)/extent of DCIS (mm). Non-parametric statistical analyses were performed to evaluate the relationship between margin index and residual DCIS. http://cancerres.aacrjournals.org/cgi/content/short/72/24_Me... The margin is reported as positive or uninvolved, with the distance to the closest margin listed (www.cap.org/cancerprotocols). http://www.cap.org/apps/cap.portal?_nfpb=true&cntvwrPtlt_act...{actionForm.contentReference}=cap_today%2F1012%2F1012b_lumpectomy_surgical.html&_state=maximized&_pageLabel=cntvwr Margin index represents a mathematical calculation [closest margin (mm)/tumor size (mm) ×100] that can reliably estimate the risk of finding residual disease in the breast following BCT for stage I–II invasive breast cancer with or without ductal carcinoma in situ (DCIS).[11] http://www.cancernetwork.com/breast-cancer/content/article/1... |
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