closest margin

English translation: Close margins: Any situation that falls between positive and negative is considered "close."

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:closest margin
Selected answer:Close margins: Any situation that falls between positive and negative is considered "close."

19:01 Mar 5, 2013
    The asker opted for community grading. The question was closed on 2013-03-09 04:54:13 based on peer agreement (or, if there were too few peer comments, asker preference.)


English language (monolingual) [PRO]
Medical - Medical (general) / Margins negative but close and the closest margin was 2.8 mm
English term or phrase: closest margin
Medical report:

Subject: breast cancer

The patient had an FNA which showed atypia. She then underwent an excisional biopsy on November 2012 and the final histology was that of a high-grade carcinosarcoma, 2 cm in size with central cystic hemorrhage, high grade and single focus. Margins negative but close and the closest margin was 2.8 mm, ER negative/PR positive at 60% and HER/neu negative by IHC.

Please provide translations based onn the given context. Thank u in advance.
sara alnuaimi
Local time: 13:23
Close margins: Any situation that falls between positive and negative is considered "close."
Explanation:

Margins, also known as "margins of resection," refer to the distance between a tumor and the edge of the surrounding tissue that's removed along with it. ...

Positive margins: Cancer cells extend out to the edge of the tissue, where the ink is.
Negative margins: No cancer cells are found in the ink.
Close margins: Any situation that falls between positive and negative is considered "close."
http://www.breastcancer.org/questions/margins
http://www.breastcancer.org/symptoms/diagnosis/margins

Other observational studies also suggest that for
DCIS, a close margin may increase the hazard of local recurrence,[15] and therefore it may be
reasonable to define the optimal free margin for DCIS as a width of 2 mm.
http://reveszmd.com/breast-cancer-surgeon-san-diego/publicat...

DCIS margin index was calculated as closest margin distance of DCIS (mm)/extent of DCIS (mm). Non-parametric statistical analyses were performed to evaluate the relationship between margin index and residual DCIS.
http://cancerres.aacrjournals.org/cgi/content/short/72/24_Me...

The margin is reported as positive or uninvolved, with the distance to the closest margin listed (www.cap.org/cancerprotocols).
http://www.cap.org/apps/cap.portal?_nfpb=true&cntvwrPtlt_act...{actionForm.contentReference}=cap_today%2F1012%2F1012b_lumpectomy_surgical.html&_state=maximized&_pageLabel=cntvwr

Margin index represents a mathematical calculation [closest margin (mm)/tumor size (mm) ×100] that can reliably estimate the risk of finding residual disease in the breast following BCT for stage I–II invasive breast cancer with or without ductal carcinoma in situ (DCIS).[11]
http://www.cancernetwork.com/breast-cancer/content/article/1...

Selected response from:

Marga Shaw
United Kingdom
Local time: 10:23
Grading comment
Many thanks
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
4 +1Close margins: Any situation that falls between positive and negative is considered "close."
Marga Shaw


  

Answers


5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
Close margins: Any situation that falls between positive and negative is considered "close."


Explanation:

Margins, also known as "margins of resection," refer to the distance between a tumor and the edge of the surrounding tissue that's removed along with it. ...

Positive margins: Cancer cells extend out to the edge of the tissue, where the ink is.
Negative margins: No cancer cells are found in the ink.
Close margins: Any situation that falls between positive and negative is considered "close."
http://www.breastcancer.org/questions/margins
http://www.breastcancer.org/symptoms/diagnosis/margins

Other observational studies also suggest that for
DCIS, a close margin may increase the hazard of local recurrence,[15] and therefore it may be
reasonable to define the optimal free margin for DCIS as a width of 2 mm.
http://reveszmd.com/breast-cancer-surgeon-san-diego/publicat...

DCIS margin index was calculated as closest margin distance of DCIS (mm)/extent of DCIS (mm). Non-parametric statistical analyses were performed to evaluate the relationship between margin index and residual DCIS.
http://cancerres.aacrjournals.org/cgi/content/short/72/24_Me...

The margin is reported as positive or uninvolved, with the distance to the closest margin listed (www.cap.org/cancerprotocols).
http://www.cap.org/apps/cap.portal?_nfpb=true&cntvwrPtlt_act...{actionForm.contentReference}=cap_today%2F1012%2F1012b_lumpectomy_surgical.html&_state=maximized&_pageLabel=cntvwr

Margin index represents a mathematical calculation [closest margin (mm)/tumor size (mm) ×100] that can reliably estimate the risk of finding residual disease in the breast following BCT for stage I–II invasive breast cancer with or without ductal carcinoma in situ (DCIS).[11]
http://www.cancernetwork.com/breast-cancer/content/article/1...



Marga Shaw
United Kingdom
Local time: 10:23
Specializes in field
Native speaker of: German
PRO pts in category: 16
Grading comment
Many thanks

Peer comments on this answer (and responses from the answerer)
agree  Veronika McLaren
2 days 12 hrs
  -> Thank you Veronika!
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