OIC

English translation: Opioid Induced Constipation

23:58 Aug 16, 2017
English language (monolingual) [PRO]
Medical - Medical: Pharmaceuticals / Clinical trials
English term or phrase: OIC
Just "OIC section", no other context is available.

Will appreciate your help with decoding this acronym.
TIA
Іnese
Ukraine
Local time: 07:11
Selected answer:Opioid Induced Constipation
Explanation:
OIC = Opioid Induced Constipation

The majority of patients treated with opioid therapy for cancer and non-cancer pain experience opioid-induced constipation (OIC). This condition is not trivial as it affects the patient's quality of life and can lead them to reduce, discontinue, or change effective analgesic therapy. The spectrum of laxative classes currently available do not provide effective results in this setting, primarily because they do not address the mechanisms by which opioids cause OIC. Research advances have improved the understanding of those underlying mechanisms and have resulted in the identification of new pharmacologic agents that target the μ-opioid receptor interaction while maintaining the analgesic benefit of the opioid and minimizing the risk of withdrawal.
http://www.mycme.com/opioid-induced-constipation-oic/section...
Selected response from:

Muhammad Said
Egypt
Local time: 06:11
Grading comment
Thank you!
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
3 +1Opioid Induced Constipation
Muhammad Said


  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
oic
Opioid Induced Constipation


Explanation:
OIC = Opioid Induced Constipation

The majority of patients treated with opioid therapy for cancer and non-cancer pain experience opioid-induced constipation (OIC). This condition is not trivial as it affects the patient's quality of life and can lead them to reduce, discontinue, or change effective analgesic therapy. The spectrum of laxative classes currently available do not provide effective results in this setting, primarily because they do not address the mechanisms by which opioids cause OIC. Research advances have improved the understanding of those underlying mechanisms and have resulted in the identification of new pharmacologic agents that target the μ-opioid receptor interaction while maintaining the analgesic benefit of the opioid and minimizing the risk of withdrawal.
http://www.mycme.com/opioid-induced-constipation-oic/section...

Muhammad Said
Egypt
Local time: 06:11
Does not meet criteria
Specializes in field
Native speaker of: Native in ArabicArabic
PRO pts in category: 4
Grading comment
Thank you!

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