médicaments « de rupture »

English translation: breakthrough drugs

13:34 Feb 16, 2020
French to English translations [PRO]
Medical - Medical: Pharmaceuticals / Policy on drug innovations
French term or phrase: médicaments « de rupture »
Hi I am translating an action sheet dealing with drug innovations.

Pour maîtriser l’évolution des dépenses dans le temps, il sera indispensable de s’appuyer sur l’anticipation, à horizon temporel large, de l’évolution de l’offre de certains médicaments « de rupture », en particulier médicaments de thérapies cellulaire et génique

Are médicaments « de rupture », "disruptive" drugs?
Sue Davis
France
Local time: 10:15
English translation:breakthrough drugs
Explanation:
https://www.google.com/search?q="breakthrough drugs"&oq="bre...
Selected response from:

Ana Vozone
Local time: 09:15
Grading comment
Many thanks for your input, I think this is the best solution. Another document I translated later had essais cliniques en rupture which I think are breakthrough trials again.
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +3breakthrough drugs
Ana Vozone
4 +1disruptive drugs
Drmanu49
4breaking-ground medicines
Marcombes (X)
4new/innovative drugs
liz askew


Discussion entries: 9





  

Answers


54 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +3
breakthrough drugs


Explanation:
https://www.google.com/search?q="breakthrough drugs"&oq="bre...

Example sentence(s):
  • Breakthrough drugs are approved based on less scientific evidence than other drugs because they are intended for people with a “serious
  • Sponsors of Breakthrough drugs meet with FDA officials early and often to ensure the most efficient possible path to approval.

    Reference: http://morningconsult.com/opinions/breakthrough-drugs-are-wo...
Ana Vozone
Local time: 09:15
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 4
Grading comment
Many thanks for your input, I think this is the best solution. Another document I translated later had essais cliniques en rupture which I think are breakthrough trials again.
Notes to answerer
Asker: Many thanks!


Peer comments on this answer (and responses from the answerer)
agree  liz askew: I think this is the one I would agree with most
4 hrs
  -> Thank you, Liz!

agree  Paola Alem
1 day 1 hr
  -> Thank you, Paola!

agree  philgoddard
1 day 15 hrs
  -> Thank you, Phil!

neutral  Drmanu49: Breakthrough does not mean disruptive or going agains previous principles
3 days 1 hr
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2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
breaking-ground medicines


Explanation:
Réellement innovants

Marcombes (X)
France
Local time: 10:15
Native speaker of: Native in FrenchFrench
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11 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
disruptive drugs


Explanation:
www.lequotidiendupharmacien.fr › actualite › medicament
Dans un contexte de maîtrise médicalisée et d'explosion de l'innovation pharmaceutique, l'arrivée de médicaments de rupture à des prix particulièrement ...

www.ddw-online.com › business › p322101-disru...
Traduire cette page
This article is part 1 of 2, and covers tools, technologies and the core model of disruptive approaches to accelerate drug discovery and development.

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Note added at 11 minutes (2020-02-16 13:45:56 GMT)
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www.optum.com › resources › advisory-insights
Traduire cette page
... considerable clinical and financial implications. These include disruptive drugs, cell and gene therapies, medical devices, procedures and other interventions.

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Note added at 13 minutes (2020-02-16 13:47:59 GMT)
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www.mba-sante.dauphine.fr › mediatheque › site › emba_sante › pdf
PDF
12 nov. 2015 - Deux questions clés. Organismes payeurs. Que souhaitent les organismes payeurs ? Médicaments de rupture. Comment financer leur accès ...

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Note added at 5 heures (2020-02-16 19:06:31 GMT)
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www.fool.com › investing › general › 2013/10/08
Traduire cette page
8 oct. 2013 - Let's begin with three recently approved drugs that have incredible potential. Three game-changing FDA-approved drugs. Eliquis -- Bristol-Myers Squibb (NYSE:BMY) and Pfizer (NYSE:PFE) Kadcyla -- ImmunoGen (NASDAQ:IMGN) and Roche. And four pipeline therapies that have worlds of potential.


Cytura Therapeutics to Develop a New Class of Drugs ...
www.cyturatherapeutics.com › News
Traduire cette page
20 mai 2019 - ... advance its first proprietary small molecule program and to further expand their pipeline of new disruptive drugs, targeting genomic instability.

Drmanu49
France
Local time: 10:15
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 1131

Peer comments on this answer (and responses from the answerer)
agree  liz askew: the more I think and research this, I see now that this term does exist and that there IS a subtle difference between "breakthrough-innovative and disruptive". Cheers!
4 hrs
  -> 3 260 Ghits for disruptive drugs in advanced search Liz.//Thank you Liz.
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5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
new/innovative drugs


Explanation:
https://europepmc.org/article/med/28057183

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Note added at 5 hrs (2020-02-16 18:52:21 GMT)
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Personally, I think "disruptive drugs" (which I am unable to find per se on line) has a negative connotation.

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Note added at 5 hrs (2020-02-16 18:53:41 GMT)
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Cell and Gene Therapy | Novartiswww.novartis.com › our-focus › cell-and-gene-therapy
Cell & Gene Therapy. We are reimagining medicine to power breakthrough innovation in cell and gene therapy. Novartis Stein, Switzerland ...

Novartis opens facility for innovative cell and gene therapies ...www.novartis.com › news › novartis-opens-facility-innovative-cell-an...
28 Nov 2019 - Novartis opens facility for innovative cell and gene therapies in ... Unlike conventional drug production, cell and gene therapy asks for the ...

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Note added at 5 hrs (2020-02-16 18:54:26 GMT)
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The FDA'S take on Medical Innovation - The Pharma Letterwww.thepharmaletter.com › article › the-fda-s-take-on-medical-innov...
18 Oct 2019 - The FDA'S take on Medical Innovation. ... on September 6, 2019, her focus was on the very high costs of innovative and breakthrough drugs.

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Note added at 3 days 1 hr (2020-02-19 14:56:06 GMT)
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innovation de rupture | WordReference Forumsforum.wordreference.com › threads › innovation-de-rupture.3171067
26 Apr 2016 - 2 posts - ‎2 authors
'Il est nettement d'y développer une innovation de rupture' ... The more common meaning is ground-breaking or breakthrough innovation.

Terminology database | gaois.iewww.gaois.ie › trm › txt=radical innovation
en discontinuous innovation | breakthrough innovation | radical innovation. DEFINITION innovation ... fr innovation radicale | innovation de rupture. DEFINITION ...

liz askew
United Kingdom
Local time: 09:15
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 465

Peer comments on this answer (and responses from the answerer)
neutral  Drmanu49: Not the same thing Liz. Innovative does not mean disruptive or going agains previous principles.
13 mins
  -> innovative is exactly that, going against the norm
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