LDL et LDL Choléstrol
| 18:44 Feb 13, 2009 |
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| French language (monolingual) [PRO] Medical - Medical (general) / Analyses cliniques | |||||||
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| SUMMARY OF ALL EXPLANATIONS PROVIDED | ||||
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| 4 | Low-density Lipoprotein and Low-Density Lipoprotein Cholesterol |
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| Summary of reference entries provided | |||
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| LDL |
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| LDL-choléstérol |
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| Discussion entries: 3 | |
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Answers
1 hr confidence: 
Low-density Lipoprotein and Low-Density Lipoprotein Cholesterol Explanation: LDL Cholesterol: At a Glance 20 May 2004 ... Overview of Low-density Lipoprotein (LDL) Cholesterol blood test, which determines risk of developing heart disease; included in a ... www.labtestsonline.org.uk/understanding/analytes/ldl.html - 43k - Cached - Similar pages -------------------------------------------------- Note added at 1 hr (2009-02-13 20:17:39 GMT) -------------------------------------------------- Normal ranges In the USA, the American Heart Association, NIH, and NCEP provide a set of guidelines for fasting LDL-Cholesterol levels, estimated or measured, and risk for heart disease. As of 2003, these guidelines were: Level mg/dL Level mmol/L Interpretation <100 <2.6 Optimal LDL cholesterol, corresponding to reduced, but not zero, risk for heart disease 100 to 129 2.6 to 3.3 Near optimal LDL level 130 to 159 3.3 to 4.1 Borderline high LDL level 160 to 189 4.1 to 4.9 High LDL level >190 >4.9 Very high LDL level, corresponding to highest increased risk of heart disease These guidelines were based on a goal of presumably decreasing death rates from cardiovascular disease to less than 2% to 3% per year or less than 20% to 30% every 10 years. Note that 100 is not considered optimal; less than 100 is optimal, though it is unspecified how much less. Over time, with more clinical research, these recommended levels keep being reduced because LDL reduction, including to abnormally low levels, has been the most effective strategy for reducing cardiovascular death rates in large double blind, randomized clinical trials;[17] far more effective than coronary angioplasty/stenting or bypass surgery. For instance, for people with known atherosclerosis diseases, the 2004 updated American Heart Association, NIH and NCEP recommendations are for LDL levels to be lowered to less than 70 mg/dL, unspecified how much lower. It has been estimated from the results of multiple human pharmacologic LDL lowering trials[citation needed] that LDL should be lowered to about 50 to reduce cardiovascular event rates to near zero. For reference, from longitudinal population studies following progression of atherosclerosis-related behaviors from early childhood into adulthood[citation needed], it has been discovered that the usual LDL in childhood, before the development of fatty streaks, is about 35 mg/dL. However, all the above values refer to chemical measures of lipid/cholesterol concentration within LDL, not LDLipoprotein concentrations, probably not the better approach. -------------------------------------------------- Note added at 1 hr (2009-02-13 20:18:35 GMT) -------------------------------------------------- Level mg/dL Level mmol/L Interpretation <100 <2.6 Optimal LDL cholesterol, corresponding to reduced, but not zero, risk for heart disease 100 to 129 2.6 to 3.3 Near optimal LDL level 130 to 159 3.3 to 4.1 Borderline high LDL level 160 to 189 4.1 to 4.9 High LDL level >190 >4.9 Very high LDL level, corresponding to highest increased risk of heart disease -------------------------------------------------- Note added at 1 hr (2009-02-13 20:19:17 GMT) -------------------------------------------------- I am not able to copy the table you require to know normal LDL levels: See: http://209.85.229.132/search?q=cache:Y-EyI2IM-v4J:en.wikiped... |
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Reference comments
11 mins |
| Reference: LDL Reference information: LDL signifie Low Density Lipoprotein en anglais , ce sont des protéines qui véhiculent le cholestérol, mais aussi des triglycérides... Tandis que LDL Cholestérol ne concerne que ces protéines qui véhiculent le cholestérol...Qui peut lui-même être véhiculé par d'autres protéines...( HDL par exemple) Reference: http://en.wikipedia.org/wiki/LDL Reference: http://www.doctissimo.fr/html/sante/analyses/ana_lipidique04... |
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30 mins |
| Reference: LDL-choléstérol Reference information: Je cite la référence : LDL-cholestérol Fraction du cholestérol sanguin associé aux LDL, calculée par différence entre le cholestérol total et le HDL-cholestérol. -> HDL-cholestérol. HDL-cholestérol Fraction du cholestérol sanguin contenu dans les HDL. Son taux plasmatique normal est de 0,35 à 0,80 g/L. Le rapport normal cholestérol total / HDL-cholestérol est de 4,5. La diminution du HDL-cholestérol est un facteur de risque d'athérosclérose et est observée chez les sujets qui en sont atteints, avec une augmentation du LDL-cholestérol (rapport cholestérol total/HDL-cholestérol > 4,5). Les hypolipémiants tendent à augmenter le HDLcholestérol (bon cholestérol) et à diminuer le LDL-cholestérol (< 2 g/L, mauvais cholestérol) et le rapport cholestérol total/ HDL-cholestérol. _________________ LDL (GDT) Domaine(s) biologie protéine low-density lipoprotein A plasma protein containing relatively more cholesterol and triacylglycerides and less protein. Syn. ß-lipoprotein Abrév. LDL V. o. low density lipoprotein ß-lipoprotéine n f Lipoprotéine du sérum sanguin formée par le foie et l'intestin, très riche en cholestérol (10 % de cholestérol libre, 38 % de cholestérol estérifié), à qui on attribue la formation des dépôts de cholestérol dans les parois des artères (athérome) et dont la densité est comprise entre 1,019 et 1,063. Note : L'absence congénitale des ß-lipoprotéines (abétalipoprotéinémie) se traduit par des troubles graves (troubles digestifs et stéatorrhée, stéatose hépatique, acanthocytose). Leur taux varie avec l'âge (comme celui de la cholestérolémie),augmentant rapidement après la naissance, puis lentement jusqu'à l'âge de 65 ans. Il est anormalement élevé chez les sujets atteints d'hypercholestérolémie xanthomateuse familiale et chez les myoedémateux, et s'abaisse sous l'influence de régimes hypocaloriques. Il est bas dans certaines populations (Bantous, Japonais). Syn. lipoprotéine de basse densité n f LDL (Emprunts, calques) Note : Abréviation de l'expression anglaise «low density lipoprotein». lipoprotéine légère n f Abrév. BLP V. o. bêtalipoprotéine n f ____________________ Le GDT donne d'autres définitions -------------------------------------------------- Note added at 31 minutes (2009-02-13 19:16:43 GMT) -------------------------------------------------- GDT = www.granddictionnaire.com La définition des LDL du site donné en référence demande une inscription préalable. Reference: http://www.informationhospitaliere.com/pharma-7650-ldl-chole... |
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