Schaltstelle
English translation: control point
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| 17:08 Nov 26, 2015 |
| German to English translations [PRO] Medical - Medical: Pharmaceuticals | |||||||
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|  Selected response from: barbarameyer | ||||||
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| Summary of answers provided | ||||
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| 4 +2 | control point |
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| 3 +1 | pivot point |
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| 1 | key location |
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| Schaltstelle > relay station |
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| Discussion entries: 3 | |
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Answers
41 mins confidence: 
key location Explanation: Is somewhat non-committing. Switching just doesn't sound right, given the context, and 'transfer points' is too specific |
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1 hr confidence: peer agreement (net): +1
peer agreement (net): +1pivot point Explanation: Works in other contexts, maybe it works here as well. |
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2 hrs confidence: peer agreement (net): +2
peer agreement (net): +2control point Explanation: schalten --> to control http://www.dict.cc/?s=Schalten Some of the many relevant references that came up when I googled for: "antiviral therapy" + "replication" + "control points" ...multiple control points exist that could be useful targets for therapeutic intervention.In particular, the tat and rev proteins, both essential for for virus replication, appear to be attractive candidates for antiviral therapy. https://goo.gl/h1KNbR The major immediate-early promoter (MIEP) of human cytomegalovirus (HCMV) is responsive to a multitude of transcription factors and plays a pivotal role in initiating the viral transcription/replication cycle...Thus, deciphering the molecular mechanisms of the MIEP regulation may reveal key control points contributing to HCMV pathogenesis. http://jvi.asm.org/content/80/19/9899.full The teleological reason for the evolution of such specific control points as targets of posttranscriptional regulation remains speculative, but one possibility is that ORF57 and related herpes virus proteins act as precise checkpoints in the temporal progression of lytic replication, preventing frequent and abortive initiation of the lytic replicative cycle. http://jvi.asm.org/content/89/3/1688.full.pdf Potent and selective inhibition of human cytomegalovirus replication by ...... Antiviral therapy in children with varicella zoster virus and herpes simplex virus ..... exploits three distinct viral signals to undermine three separate control points in ... http://www.asmscience.org/content/book/10.1128/9781555815974... -------------------------------------------------- Note added at 11 hrs (2015-11-27 04:35:45 GMT) -------------------------------------------------- Der Hypothalamus ist die zentrale Schaltstelle zur Regulation des inneren Milieus und gleichzeitig die oberste Instanz der Hormonregulation des menschlichen ... https://goo.gl/LLu2fn Regulation of Thyrotropin Releasing Hormone (TRH) transcription in the hypothalamus represents the central control point of thyroid function. http://www.sciencedirect.com/science/article/pii/S0014579304... The hypothalamus is the control point that maintains our body temperature between 96.8°F and 100.4°F. http://essentialsofcorrectionalnursing.com/2015/02/17/vital-... |
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1 hr |
| Reference: Schaltstelle > relay station Reference information: The first therapy which inhibits viral replication at three key ***relay stations*** and evidences a high resistance barrier references: Localization of a relay station for the depressor reflex in the medulla ... www.researchgate.net/.../279701193_Localization_of_a_relay_... Publication » Localization of a ***relay station*** for the depressor reflex in the medulla oblongata in rabbits. [Lokalisation einer ***Schaltstelle*** für den Depressorreflex in ... Parasympathikus – Wikipedia https://de.wikipedia.org/wiki/Parasympathikus Die Umschaltung erfolgt an ***Schaltstellen üblicher Art (chemische Synapsen)*** durch Abgabe (Exozytose) von Signalmolekülen (Neurotransmittern) von Zelle A ... Fundamentals of Neurophysiology - Page 72 - https://books.google.com/books?isbn=3662011549 Robert F. Schmidt - 2013 - Medical In this type, the axonal ending when stimulated releases a chemical ... That is, ***synapses act primarily as one-way relay stations***, both between neurons and ... Neuroscience in Medicine - Page 95 - https://books.google.com/books?isbn=1603274553 P.Michael Conn - 2008 - Medical PROPERTIES OP CHEMICAL AND ELECTRICAL SYNAPSES A MODEL SYNAPsE: THE ... For example, many ***synapses function as high-fidelity relay stations***. Physiology Exam 2 flashcards | Quizlet https://quizlet.com/71967038/physiology-exam-2-flash-cards/ Which of the below structures in the brain acts as a ***synaptic relay station*** for sensory ... The strength with which a chemical messenger binds to its receptor. -------------------------------------------------- Note added at 1 hr (2015-11-26 18:21:36 GMT) -------------------------------------------------- Molecular Mechanisms Of Drug Action - https://books.google.com/books?isbn=0748400680 Christopher J. Coulson - 1994 - Medical A zone of lysis, known as a plaque, is then formed wherever replicating viral ... When latent, herpesvirus 1 resides in ***the trigeminal ganglion (a relay station*** for ... Advances in Understanding Mechanisms of Thalamic Relays in ... www.jneurosci.org/content/34/46/15340.full 12 Nov 2014 ... Inhibitory inputs may be another form of modulation because these affect ... the ***dorsal midline and intralaminar complex can serve as relay stations*** ..... system: ultrastructural characterization of viral replication, transport, and ... Swanton, C. et al. Herpes viral cyclin-CDK6 complexes evade ... www.researchgate.net/.../13863033_Swanton_C._et_al._Herpes_... 22 Jul 2014 ... Herpes viral cyclin-CDK6 complexes evade inhibition by CDK ... that involve many ***relay stations*** (Figure 3) to convey a cell proliferation signal ... Human Phys Final - StudyBlue https://www.studyblue.com/notes/note/n/human-phys-final/.../... May 6, 2015 - Which sensory system does not use the ***thalamus as a relay station*** in the brain. Olfaction ... Lateral inhibition. Order of .... Inhibit viral replication. |
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