Spendermobiliseurung
English translation: donor mobilization
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| 14:50 May 29, 2017 |
| German to English translations [PRO] Medical - Medical: Pharmaceuticals / clinical studies on Zalmoxis | |||||||
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|  Selected response from: andres-larsen Venezuela Local time: 13:05 | ||||||
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| 4 | donor rate (response) |
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| 2 +1 | poor mobilizers |
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| 3 | as they didn't react well to the donor treatment |
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| 1 | donor mobilization |
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| Summary of reference entries provided | |||
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| bei Spendern für Transplantation mobilisierte Stammzellen |
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Answers
5 hrs confidence: 
peer agreement (net): +1
peer agreement (net): +1| schlechte Spendermobilisierung poor mobilizers Explanation: Unusual wording – possibly refers to the fact that with autologous SCT, the patient is donor and recipient of the stem cell transplant. In other words, these patients did not mobilize enough stem cells for harvest in their "donor phase", hence did not receive enough stem cells in their "recipient phase" and relapsed early. Aunty G seems to know just one single reference for "Spendermobilisierung" in that sense: "... und mehrere klinische Fachverbände empfehlen derzeit, Biosimilar G-CSF für die Spendermobilisierung nur im Rahmen klinischer Studien anzuwenden" https://www.thieme-connect.de/products/.../s-0032-1325071?la... Otherwise, "Spendermobilisierung" always refers to donor recruitment campaigns. |
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9 hrs confidence:
donor rate (response) Explanation: Patients being affected by a poor donor/donation rate or response |
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10 hrs confidence:
as they didn't react well to the donor treatment Explanation: I think this is the idea -------------------------------------------------- Note added at 10 hrs (2017-05-30 01:07:41 GMT) -------------------------------------------------- and suffrered an early relapse -------------------------------------------------- Note added at 10 hrs (2017-05-30 01:09:59 GMT) -------------------------------------------------- oops should read "suffered" -------------------------------------------------- Note added at 10 hrs (2017-05-30 01:13:02 GMT) -------------------------------------------------- and your own "respond" is fine |
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2 hrs confidence:
donor mobilization Explanation: Healthy donor hematopoietic stem cell mobilization with biosimilar ... onlinelibrary.wiley.com/doi/10.1111/trf.13853/full - P Becker - 2016 - 16 sep. 2016 - Healthy donor hematopoietic stem cell mobilization with biosimilar granulocyte-colony-stimulating factor: safety, efficacy, and graft performance ... AMD3100 to Mobilize Stem Cells for Donation - Full Text View ... https://clinicaltrials.gov/ct2/show/NCT00075335 Although regimens using G-CSF usually succeed in collecting adequate numbers of PBPC from healthy donors, 5%-10% will mobilize stem cells poorly and may ... Mobilization of blood stem cells - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/stem.5530160817/pdf A Kessinger - 1998 - Some autologous blood stem cell donors exhibit indifference to currently applied mobilization therapies. This failure to mobilize has been associated with. G-CSF in Healthy Allogeneic Stem Cell Donors - NCBI - NIH https://www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC) - K Hölig - 2013 - Pasar a G-CSF Dosing and Factors Affecting Mobilization Efficacy - Donors not mobilizing adequate numbers of CD34+ cells after G-CSF administration ... -------------------------------------------------- Note added at 2 hrs (2017-05-29 17:07:15 GMT) -------------------------------------------------- G-CSF in Healthy Allogeneic Stem Cell Donors - NCBI - NIH https://www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC) - K Hölig - 2013 - G-CSF Dosing and Factors Affecting Mobilization Efficacy - Donors not mobilizing adequate numbers of CD34+ cells after G-CSF administration ... -------------------------------------------------- Note added at 2 hrs (2017-05-29 17:09:39 GMT) -------------------------------------------------- Mobilization of healthy donors with plerixafor affects the cellular ... https://translational-medicine.biomedcentral.com/.../s12967-... - S Rutella - 2014 - 2 sep. 2014 - Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem ... -------------------------------------------------- Note added at 2 hrs (2017-05-29 17:10:19 GMT) -------------------------------------------------- Mobilization of healthy donors with plerixafor affects the cellular ... https://translational-medicine.biomedcentral.com/.../s12967-... - S Rutella - 2014 - 2 sep. 2014 - Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem ... -------------------------------------------------- Note added at 3 days3 hrs (2017-06-01 18:13:28 GMT) Post-grading -------------------------------------------------- Glad to have been of help, Stephen |
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Reference comments
2 hrs |
| Reference: bei Spendern für Transplantation mobilisierte Stammzellen Reference information: Mobilisierte Blutstammzellen in der Stammzelltransplantation https://www.deutsche-apotheker-zeitung.de/.../mobilisierte-b... 4 nov. 2010 - In der Regel mobilisiert eine Behandlung über fünf Tage hinweg bei rund 80% der Spender genügend Stammzellen für die Transplantation eines erwachsenen Patienten; ein weiterer Tag unter G-CSF-Gabe führt bei annähernd 99% der Spender zu einer ausreichenden Stammzellbildung. -------------------------------------------------- Note added at 2 hrs (2017-05-29 17:01:19 GMT) -------------------------------------------------- Mobilization of Hematopoietic Stem/Progenitor Cells: Mobilisierung hämatopoietischer Stammzellen - Thieme E-Books & E ... https://www.thieme-connect.com/products/.../s-0032-1325071?.... - Georg Thieme Verlag KG Stuttgart · New York. Mobilisierung hämatopoietischer Stammzellen. Mobilization of Hematopoietic Stem/Progenitor CellsD. Karpova, ... Protocols and Video Articles Authored by Laurence J.N. Cooper ... www.jove.com/author/Laurence J.N._Cooper?language... Allogene HSCT ist die zuverlässige, robuste und effektive zellbasierte .... Ausbau Pools der Spender, Mobilisierung und Ernte hämatopoetische Stammzellen, ... -------------------------------------------------- Note added at 2 hrs (2017-05-29 17:04:39 GMT) -------------------------------------------------- AMD3100 to Mobilize Stem Cells for Donation - Full Text View ... https://clinicaltrials.gov/ct2/show/NCT00075335 Although regimens using G-CSF usually succeed in collecting adequate numbers of PBPC from healthy donors, 5%-10% will mobilize stem cells poorly and may ... Mobilization of blood stem cells - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/stem.5530160817/pdf A Kessinger - 1998 - Some autologous blood stem cell donors exhibit indifference to currently applied mobilization therapies. This failure to mobilize has been associated with. G-CSF in Healthy Allogeneic Stem Cell Donors - NCBI - NIH https://www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC) - K Hölig - 2013 - Pasar a G-CSF Dosing and Factors Affecting Mobilization Efficacy - Donors not mobilizing adequate numbers of CD34+ cells after G-CSF administration ... |
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