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vale

English translation: Valley (or trough)

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Portuguese term or phrase:vale
English translation:Valley (or trough)
Entered by: Paulo Eduardo - Pro Knowledge

08:11 Aug 27, 2017
Portuguese to English translations [PRO]
Medical - Medical (general) / alpha-1 antitrypsin deficiency
Portuguese term or phrase: vale
I can't figure out what it means in this context, so any help would be appreciated.

'... sendo mais expressivo nos doentes com maior concentração AAT em vale.
A concentração de vale, atingida durante o tratamento, foi maior nos doentes com maior peso e com maior concentração no pré-tratamento.'

Thanks in advance for your help!
Tania Pires
Portugal
Local time: 08:46
Valley (concentrations)
Explanation:
opposed to peak concentrations

https://openi.nlm.nih.gov/detailedresult.php?img=PMC3742415_...
Selected response from:

Paulo Eduardo - Pro Knowledge
Brazil
Local time: 04:46
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +5Valley (concentrations)
Paulo Eduardo - Pro Knowledge
5 +1trough
BNN Medical Tr.


  

Answers


20 mins   confidence: Answerer confidence 5/5 peer agreement (net): +5
Valley (concentrations)


Explanation:
opposed to peak concentrations

https://openi.nlm.nih.gov/detailedresult.php?img=PMC3742415_...

Paulo Eduardo - Pro Knowledge
Brazil
Local time: 04:46
Native speaker of: Native in EnglishEnglish, Native in PortuguesePortuguese
PRO pts in category: 24
Notes to answerer
Asker: Thanks, Paulo!


Peer comments on this answer (and responses from the answerer)
agree  Maria Teresa Borges de Almeida
1 hr
  -> Obrigado Teresa
agree  Margarida Ataide
1 hr
  -> Obrigado Margarida
agree  Salvador Scofano and Gry Midttun
3 hrs
  -> Obrigado Salvador
agree  Mario Freitas:
8 hrs
  -> Obrigado Mario. Desnecessário. A vida se encerregará disso.
agree  Oliver Simões
12 hrs
  -> Obrigado Oliveira
Login to enter a peer comment (or grade)

5 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
trough


Explanation:
Em farmacocinética, se diz "trough concentration" ou "trough level" para a concentração mais baixa observada de um medicamento na corrente sanguínea, que é traduzido como "concentração de vale". Uma pesquisa Google para "valley concentration" retornou 4.700 resultados, vs. 90.500 para "trough concentration". A mesma pesquisa no ClinicalTrials.gov retornou 0 resultados para "valley concentration" e 905 resultados para "trough concentration". Note que deve-se sempre usar as aspas nessas pesquisas para que não se considere cada termo isoladamente e retorne resultados para coisas como "Silicon Valley".


    https://www.google.com.br/search?q="trough+concentration"&oq="trough+concentration"
BNN Medical Tr.
Brazil
Local time: 04:46
Specializes in field
Native speaker of: Native in PortuguesePortuguese

Peer comments on this answer (and responses from the answerer)
agree  Katarina Peters
36 mins
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