Glossary entry (derived from question below)
English term or phrase:
13q gain
Russian translation:
увеличение материала 13q
Added to glossary by
cherepanov
Nov 29, 2017 11:35
6 yrs ago
English term
13q gain
English to Russian
Science
Biology (-tech,-chem,micro-)
DIS3 was shown to be up-regulated in colorectal carcinomas through a 13q gain.
О делеции в этом гене нашел информацию, а здесь что происходит?
Спасибо!
О делеции в этом гене нашел информацию, а здесь что происходит?
Спасибо!
Proposed translations
(Russian)
3 | увеличение материала 13q | Igor Andreev |
4 | хромосомная перестройка 13q c прибавлением генетического материала | Margarita Vidkovskaia |
Proposed translations
7 hrs
Selected
увеличение материала 13q
увеличение материала на длинном плече 13 хромосомы
4 KudoZ points awarded for this answer.
Comment: "Спасибо!"
3 hrs
хромосомная перестройка 13q c прибавлением генетического материала
относится к несбалансированным хромосомным перестройкам
механизмы прибавки материала могут быть разные (см. ниже)
https://academic.oup.com/hmg/article/23/R1/R76/2900848
The impact of chromosomal rearrangements on regulation of gene expression
Chromosome rearrangements occur in two broad forms—balanced and unbalanced. Balanced, or copy number neutral, refers to those in which there is no net gain or loss of genetic material, though some rearrangement has occurred—this includes reciprocal translocations and inversions. Unbalanced rearrangements are those in which genetic material is either gained or lost and can include copy number variant (CNV) regions, caused by deletions or duplications, or the inheritance of unbalanced translocation products (Figs. 1 and 2). Both types of rearrangement have been shown to have impacts on gene expression through a variety of different mechanisms, some of which are outlined in this review.
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Note added at 3 hrs (2017-11-29 15:30:14 GMT)
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К сожалению, не знаю, как это называют по-русски коротко.
механизмы прибавки материала могут быть разные (см. ниже)
https://academic.oup.com/hmg/article/23/R1/R76/2900848
The impact of chromosomal rearrangements on regulation of gene expression
Chromosome rearrangements occur in two broad forms—balanced and unbalanced. Balanced, or copy number neutral, refers to those in which there is no net gain or loss of genetic material, though some rearrangement has occurred—this includes reciprocal translocations and inversions. Unbalanced rearrangements are those in which genetic material is either gained or lost and can include copy number variant (CNV) regions, caused by deletions or duplications, or the inheritance of unbalanced translocation products (Figs. 1 and 2). Both types of rearrangement have been shown to have impacts on gene expression through a variety of different mechanisms, some of which are outlined in this review.
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Note added at 3 hrs (2017-11-29 15:30:14 GMT)
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К сожалению, не знаю, как это называют по-русски коротко.
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