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All this is not without medical significance. On the one hand is the finding of Chizevsky in the 1920s (which has recently been confirmed) that animals deprived of negative ions in the air became sick and died within days. On the other is the long tradition of successful therapy with ozone and hydrogen peroxide.
It turns out that negative ions are in fact superoxide anion radicals, and that a regular supply of ROS from the environment is required to "spark" the internal mechanism of oxygen reduction. Without this, the oscillations in ROS metabolism tend to decay. And then,
with insufficient ROS, the radical chain reactions proceed without proper termination and go on to damage biological molecules.