Oct 13, 2010 18:03
13 yrs ago
3 viewers *
German term

schlechte Verträglichkeit

German to English Medical Medical: Pharmaceuticals Patient leaflet
Was tun Sie bei schlechter Verträglichkeit unter Penizillin?

Intolerance is often used, but I'm not sure it actually expresses the same as "schlechte" tolerance.
Change log

Oct 13, 2010 18:57: Steffen Walter changed "Field (write-in)" from "Patient leaftlet" to "Patient leaflet"

Proposed translations

+1
31 mins
Selected

poor tolerance

as opposed to intolerance
Peer comment(s):

agree casper (X) : "Poor drug tolerance" is the phrase that comes to my mind. // Well, well, I simply said that the phrase comes to my mind. Period.
9 hrs
I don't think drug should be in the expression because it is not there in the German
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4 KudoZ points awarded for this answer. Comment: "Thanks to everyone! I decided to go with this one :-)"
+1
2 mins

adverse reactions

Not so sure, though
Peer comment(s):

agree Raghunathan Rajagopalan : adverse drug reactions
5 hrs
Thank you, Raghunathan.
Something went wrong...
+4
8 mins

intolerance

Drug intolerance or drug sensitivity is a lower threshold to the normal pharmacologic action of a drug.
Peer comment(s):

agree Evan Wilson : poor intolerance
4 mins
Thanks!
agree Susanne Schiewe : poor tolerance; intolerance = Unverträglichkeit
9 mins
Thanks!
agree jccantrell : I would just use intolerance because that is negative by itself.
24 mins
Thanks!
agree Lirka : but would advise against 'poor intolerance' (see above)
4 hrs
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+3
51 mins

poor tolerability


"poor tolerability" is widely used in clinical trials.

Dose reductions of docetaxel and cisplatin due to poor tolerability were necessary in 3 pts (11%).
http://meeting.ascopubs.org/cgi/content/abstract/24/18_suppl...

The tendency of clinical experts to try to demonstrate superiority of one drug over another by using doses higher than patients really need must be resisted. The price paid in poor tolerability exceeds any potential benefits.
http://www.springerlink.com/content/n67213620t50h7j0/





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Note added at 57 mins (2010-10-13 19:01:18 GMT)
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The following events were considered to be treatment failures: (1) progressive growth of any treated skin lesion according to the WHO definition; (2) development of any new lesions within an adequately treated area; (3) withdrawal of the patient because of poor tolerability of the study medication;
http://jco.ascopubs.org/content/19/21/4150.full
Peer comment(s):

agree MMUlr : this is correct IMO / see also: http://journals.lww.com/pidj/Fulltext/2004/02001/Evaluation_...
24 mins
Thank you, MMUlr, also for the additional link!
agree Siegfried Armbruster
10 hrs
Thank you, Siegfried!
agree Judith Shiozawa (X)
13 hrs
Thank you, jashio!
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