English to Lithuanian Medical Medical: Pharmaceuticals Genotypes

Patients who are carriers of the SLCO1B1 c.521T>C genotype are at increased risk of myopathy. Homozygote C allele carriers (also called CC) treated with a high drug dose have a 15% risk of myopathy within one year, while the risk in heterozygote C allele carriers (CT) is 1.5%.