English to French Medical Genetics

(I thought "liaison" but that doesn't seem to be it.)

Schematic representation of the pentameric form of IgM with the ***“J” joining chain***.

In the differentiation of an immature B-cell to an antibody-forming plasma cell, the V and C gene segments of the kappa light chains are joined by a short section of DNA called the ***joining (J) segment*** (not to be confused with the J chain of IgM).

A B-cell must therefore complete two DNA rearrangement events or transpositions.
It must first bring together one DH and one JH segment and then attach these to a VH segment.
This is called ***VDJ joining.***
There can be some imprecision in the VJ and VDJ ***joining*** process, such that the site at which one segment fuses with the other can vary slightly.