English to Russian Law/Patents Medical: Instruments

The invention was based on unexpected findings that agents can be safely and predictably delivered at therapeutic or prophylactic levels to specific tissues, *even in a local context* , through the control of the organ surface exposed to an agent as well as by control of the agent's exposure to the internal body tissues and fluids. This can be achieved by maintaining the organ interface permeable to the agent through osmotic agents, physical, chemical or biological treatment, and by isolating and localizing the interface area of exchange through a sealing mechanism.