English to Russian Medical Medical: Health Care Role of Laboratory in Disease Surveillance

Planning a Strategy for Laboratory Investigations
Adapted sampling

Who to sample?

Cases
-“typical” cases
-cases likely to carry the pathogen (e.g. children)
-untreated patients (e.g. without antibiotics)
-outliers (e.g. demographic, geographic)
Controls
-laboratory controls to check that the test is indeed negative
-controls from a case-control study to check to confirm diagnosis (not infected)

All subjects or a representative sample?