Uteri are best received unfixed, particularly
in patients with cancer. Not only can appropriate tissue be selected and optimally
processed for special investigations, including
hormone receptors, electron microscopy,
cytology imprints and some types of immunohistochemistry, but the fresh specimen is better for macroscopic description and preparation for demonstration at clinicopathological meetings and macrophotography.
Endometrial autolysis occurs rapidly when
incompletely opened or unopened uteri have
been left in fixative in the operating
theatre or laboratory. Formalin penetrates
solid tissue very slowly from the exterior, and
for practical purposes does not enter the uterine cavity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC501242/pdf/jcli...

Co to jest sekcja zamrożona?
Zamrożony skrawek to sposób, w jaki patolog może bardzo szybko zbadać próbkę tkanki pod mikroskopem. Inne nazwy sekcji mrożonych to szybki przekrój i konsultacja śródoperacyjna.

https://www.mypathologyreport.ca/pl/pathology-dictionary/fro...

Dostarczanie próbek do laboratorium
Zastanów się, ile czasu zajmie dostarczenie ich do laboratorium. Oddziel tkanki utrwalone od świeżych

https://www.3trzy3.pl/artykuły/praktyczne-wskazowki-dotycząc...

1.51: FROZEN SECTION SPECIMEN COLLECTION—UNFIXED
Place the tissue into a clean, empty container or on a moist towel so that the tissue does not dry out. Tissue removed for frozen section rapid pathologic diagnosis must not be placed into formalin or any other fixative. It must be submitted fresh and moist.
Make sure there is sufficient tissue so that both a frozen section sample and a sample for permanent sectioning and routine examination are possible.
Include the TELEPHONE NUMBER where you want the frozen section diagnosis to be called. - https://www.ocpath.com/specimen-collection/

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What is fresh frozen sample?

Fresh Frozen Tissue Collection

Tissues are snap-frozen in liquid nitrogen within 30 to 60 minutes of surgery excision. Standard sample weight is 0.5 – 1.0 gram. Samples can be collected/embedded in Optimal Cutting Temperature (OCT) media upon request. Tissues are stored in vapor-phase liquid nitrogen (-190°C). - https://www.proteogenex.com/biorepository/human-tissue-speci...

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Note added at 2 days 4 hrs (2023-07-12 18:08:42 GMT)
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Fresh Tissue
Any specimen requiring an intraoperative consultation (or frozen section), ancillary studies (e.g. flow cytometry, chromosome analysis and/or special send out testing), and muscle biopsies should be submitted "fresh" without fixative. Such tissues should be delivered immediately to the Frozen Section Suite, SESP Room 3P508 between the hours of 8:00 a.m. and 5:00 p.m. After hours, and on weekends and holidays, contact the Pathology resident on call for handling of these tissues. - https://health.ucdavis.edu/pathology/services/clinical/anato...