Nov 25, 2019 09:06
4 yrs ago
2 viewers *
English term
PHARMACY - LIFE SCIENCES
Native in: Russian
Works in: English to Russian, Russian to English
fluorescent probe exclusion assays
English to Russian
Medical
Medical: Pharmaceuticals
Stabilization values averaged between Western blot and fluorescent probe exclusion assays (except Diflunisal, which includes only Western blot); tafamidis either purchased commercially or synthesized for research use
NIS=Neuropathic Impairment Score; NIS-LL=NIS of Lower Limbs; NIS+7=NIS plus 7 nerve tests; mNIS+7=modified NIS plus 7 nerve tests
NIS=Neuropathic Impairment Score; NIS-LL=NIS of Lower Limbs; NIS+7=NIS plus 7 nerve tests; mNIS+7=modified NIS plus 7 nerve tests
Proposed translations
(Russian)
| 4 | здесь: результаты экспериментов по исключению флуоресцентной метки |
Natalie
|
| 4 | тест с ингибированием связывания флуоресцентной метки |
Igor Andreev
|
Proposed translations
36 mins
Selected
здесь: результаты экспериментов по исключению флуоресцентной метки
Эксперименты, позволяющие определить занятость участков связывания.
4 KudoZ points awarded for this answer.
Comment: "Спасибо!"
6 hrs
Igor Andreev
Native in Russian
Native in: Russian 
Works in: English to Russian, Ukrainian to Russian, English to Ukrainian
Related KudoZ points
:
625
тест с ингибированием связывания флуоресцентной метки
я бы все же назвал это так
см. описание метода:
FPE assay for binding TTR in buffer and human or dog serum.
The binding affinity and selectivity of AG10 and other stabilizers to TTR in buffer and serum was determined by their ability to compete with the binding of a fluorescent probe exclusion (FPE probe) binding to TTR in buffer and human serum.18 The FPE probe is a thioester TTR ligand (Supplementary Figure 1) that is not fluorescent by itself, however upon binding to the T4 binding site of TTR it covalently modifies lysine 15 (K15), creating a fluorescent conjugate.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276790/
см. описание метода:
FPE assay for binding TTR in buffer and human or dog serum.
The binding affinity and selectivity of AG10 and other stabilizers to TTR in buffer and serum was determined by their ability to compete with the binding of a fluorescent probe exclusion (FPE probe) binding to TTR in buffer and human serum.18 The FPE probe is a thioester TTR ligand (Supplementary Figure 1) that is not fluorescent by itself, however upon binding to the T4 binding site of TTR it covalently modifies lysine 15 (K15), creating a fluorescent conjugate.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276790/
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