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Jun 29, 2020 13:07
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English term

intra-hepatic host-mediated mutagenicity test

English to Russian Medical Medical: Pharmaceuticals генотоксично�
Negative results were obtained in a dominant lethal test in male Wistar rats (0 %, 1 %, or 5 % ascorbic acid in diet for 2 weeks), a micronucleus test in CBA mice (5 % in drinking water for 41 d), an in vivo mutagenicity test in bone marrow of Chinese hamsters (200 to 10,000 mg/kg b.w. i.p. and p.o.), an intra-hepatic host-mediated mutagenicity test in guinea pigs (2 - 5,000 mg/kg b.w. ascorbic acid for 4 weeks in diet; S. typhimurium was injected i.v.)
References
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Proposed translations

19 hrs

внутрипеченочный опосредованный хозяином тест на мутагенность

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Reference comments

24 mins
Reference:

see

(PDF) Genotoxic effects of N-nitrosodimethylamine in somatic ...www.researchgate.net › publication- Translate this page
... г. в тесте с млекопитаю-. щим-посредником (host-mediated assay) было показано, ... Organ variation in. the mutagenicity of dimethylnitrosamine in Big Blue.

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Note added at 26 mins (2020-06-29 13:33:42 GMT)
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в Н «Н .Хромов-Борюов о л ФИЗИОЛОГИЧЕСКАЯ ТЕОРИЯ ...dspace.spbu.ru › 16_Khromov-borisov
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среды ( Ames е.а., 1973; Carcinogens..., 1973). Убедительные доказательства ... ванного хозяином" (host mediated assay ). В этих опытах обнаружены та.
by NN Khromov-Borisov - ‎1976

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Note added at 29 mins (2020-06-29 13:37:00 GMT)
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https://cyberleninka.ru/article/n/modelirovanie-podhodov-k-i...
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