Glossary entry (derived from question below)
English term or phrase:
low substituted
Serbian translation:
niskog stepena supstitucije
Added to glossary by
Aleksandar Skobic
May 28, 2011 10:47
12 yrs ago
1 viewer *
English term
low substituted
English to Serbian
Medical
Medical: Pharmaceuticals
Each gastro-resistant hard capsule contains 20mg omeprazole and excipient: hypromel-lose, disodium hydrogen phosphate dehydrate, sodium lauryl, sulphate, low substituted, hydroxyl propyl cellolose, sugar spheres, titanium dioxide (E171), magnesium carbonate light, talc, methacrylic acid copolymer type.
Proposed translations
(Serbian)
3 +3 | niskog stepena supstitucije | Sladjana Daniels |
5 | nizak stepen zamene u hidroksipropil celulozi | Zorica Djurkovic |
1 +1 | nisko supstituirana | ipv |
Proposed translations
+3
2 hrs
Selected
niskog stepena supstitucije
Ne bi trebalo da ima zarez, to je hidroksipropil celuloza niskog stepena supstitucije, na engleskom L-HPC. Ali ovo je samo moje objašnjenje, nažalost ne znam tačno kako farmaceuti to zovu kod nas.
http://www.galenika.rs/index.php?option=com_content&task=vie...
Sadržaj pomoćnih supstanci:
Sadržaj jezgra tablete: mikrokristalna celuloza; laktoza, monohidrat; skrob, kukuruzni, preželatinizovan; natrijum-skrob glikolat; magnezijum-stearat
Sadržaj filma-Opadry white: hidroksipropil celuloza; hipromeloza; titan-dioksid (E171)
http://www.doiserbia.nb.rs/img/doi/0367-598X/2010/0367-598X1...
Uzorci karboksimetil-skroba imaju stepene supstitucije 0,50 i 0,70 i molarne mase 5,06×10o6 i 15,4×10o6 g/mol, a uzorak katjonskog skroba ima stepen supstitucije 0,30 i molarnu masu od 19,2×10o6 g/mol.
http://www.galenika.rs/index.php?option=com_content&task=vie...
Sadržaj pomoćnih supstanci:
Sadržaj jezgra tablete: mikrokristalna celuloza; laktoza, monohidrat; skrob, kukuruzni, preželatinizovan; natrijum-skrob glikolat; magnezijum-stearat
Sadržaj filma-Opadry white: hidroksipropil celuloza; hipromeloza; titan-dioksid (E171)
http://www.doiserbia.nb.rs/img/doi/0367-598X/2010/0367-598X1...
Uzorci karboksimetil-skroba imaju stepene supstitucije 0,50 i 0,70 i molarne mase 5,06×10o6 i 15,4×10o6 g/mol, a uzorak katjonskog skroba ima stepen supstitucije 0,30 i molarnu masu od 19,2×10o6 g/mol.
4 KudoZ points awarded for this answer.
+1
2 hrs
nisko supstituirana
moglo bi biti, ali naglašavam da je confidence level 1 :)
Pomoćne tvari su: míkrokristalna celuloza, manitol, krospovidon, nisko supstituirana hidroksipropilceluloza, aspartam, kalcij-silikat..
www.almp.hr/upl/lijekovi/PIL/UP-I-530-09-06-01-30.pdf
(LH-21); hidroksipropilceluloza, nisko supstituirana(LH-11); talk, makrogol ...
www.almp.hr/upl/lijekovi/PIL/UP-I-530-09-07-01-517.pdf
Pomoćne tvari su: míkrokristalna celuloza, manitol, krospovidon, nisko supstituirana hidroksipropilceluloza, aspartam, kalcij-silikat..
www.almp.hr/upl/lijekovi/PIL/UP-I-530-09-06-01-30.pdf
(LH-21); hidroksipropilceluloza, nisko supstituirana(LH-11); talk, makrogol ...
www.almp.hr/upl/lijekovi/PIL/UP-I-530-09-07-01-517.pdf
Peer comment(s):
agree |
Dragana Samardžijević
: "... manitol, nisko-supstituiranu hidroksipropilcelulozu i barem jedan lubrikant izabran između makrogola, talka i hidriranog ricinusovog ulja. ..."www.dziv.hr/webcontent/file_library/izvori_inf/.../05_2010.... (mada se ne može ući, postojao je trag)
19 mins
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hvala
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2 days 6 hrs
nizak stepen zamene u hidroksipropil celulozi
1)Product name:Low-substituted hydroxypropyl cellulose
Product description:The present invention provides low-substituted hydroxypropyl cellulose exhibiting good granulation characteristics and tablet properties. Specifically, there is provided low-substituted hydroxypropyl cellulose having a hydroxypropoxyl content in the range of 5.0 to 16.0% by weight and an apparent average degree of polymerization in the range of 350 to 700
2)Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility. It is used as a topical ophthalmic protectant and lubricant.
HPC is an ether of cellulose in which some of the hydroxyl groups in the repeating glucose units have been hydroxypropylated forming -OCH2CH(OH)CH3 groups using propylene oxide. The average number of substituted hydroxyl groups per glucose unit is referred to as the degree of substitution (DS). Complete substitution would provide a DS of 3. Because the hydroxypropyl group added contains a hydroxyl group, this can also be etherified during preparation of HPC. When this occurs, the number of moles of hydroxypropyl groups per glucose ring, moles of substitution (MS), can be higher than 3.
Product description:The present invention provides low-substituted hydroxypropyl cellulose exhibiting good granulation characteristics and tablet properties. Specifically, there is provided low-substituted hydroxypropyl cellulose having a hydroxypropoxyl content in the range of 5.0 to 16.0% by weight and an apparent average degree of polymerization in the range of 350 to 700
2)Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility. It is used as a topical ophthalmic protectant and lubricant.
HPC is an ether of cellulose in which some of the hydroxyl groups in the repeating glucose units have been hydroxypropylated forming -OCH2CH(OH)CH3 groups using propylene oxide. The average number of substituted hydroxyl groups per glucose unit is referred to as the degree of substitution (DS). Complete substitution would provide a DS of 3. Because the hydroxypropyl group added contains a hydroxyl group, this can also be etherified during preparation of HPC. When this occurs, the number of moles of hydroxypropyl groups per glucose ring, moles of substitution (MS), can be higher than 3.
Reference:
http://en.wikipedia.org/wiki/Hydroxypropyl_cellulose
http://www.godowell.com/Biochemical-series/Low-substituted-hydroxypropyl-cellulose/
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