Nov 6, 2018 10:17
5 yrs ago
4 viewers *
English term
Traductora Pública de Inglés
Native in: Spanish
Works in: English to Spanish, Spanish to English
ligand protein
English to Spanish
Law/Patents
Patents
ligand protein
In some preferred embodiments, the disclosure features BFP3 format bispecific fusion proteins including one or more N-terminus antigen binding subunits, a central Fc polypeptide core, and one or more C-terminus ligand proteins.
In one embodiment, the one or more N-terminus antigen binding subunits (BD2) can be anti-PD-1 and/or anti-PD-1L antigen binding subunits, the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL, OX40L, CD40L, TNF-α, and/or CD137.
No me queda claro si es proteína ligando directamente.
https://es.wikipedia.org/wiki/Acoplamiento_molecular
MUCHAS GRACIAS
In one embodiment, the one or more N-terminus antigen binding subunits (BD2) can be anti-PD-1 and/or anti-PD-1L antigen binding subunits, the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL, OX40L, CD40L, TNF-α, and/or CD137.
No me queda claro si es proteína ligando directamente.
https://es.wikipedia.org/wiki/Acoplamiento_molecular
MUCHAS GRACIAS
Proposed translations
(Spanish)
| 4 +3 | proteína ligando |
Maria Iglesia Ramos
|
| 3 | proteína ligante |
maría bergós
|
| 3 | dominio [proteína] de unión a ligando C-terminal |
Chema Nieto Castañón
|
| 3 | proteína ligando |
Clara Bugallo
|
Proposed translations
+3
1 hr
Maria Iglesia Ramos
Spain
Spain
Native in Spanish
Works in field
Spain
Also an interpreter (medical, court)
Native in: Spanish 
Works in: English to Spanish, Spanish to English, French to Spanish, and 3 more.
Related KudoZ points
:
4
Selected
proteína ligando
Es como se conoce.
4 KudoZ points awarded for this answer.
Comment: "Selected automatically based on peer agreement."
1 hr
3 hrs
Chema Nieto Castañón
Spain
Spain
Native in Spanish
Spain
Psychologist & Emergency Physician
Native in: Spanish (Variant: Standard-Spain)
Works in: English to Spanish
Related KudoZ points
:
4
English term (edited):
C-terminus ligand protein
dominio [proteína] de unión a ligando C-terminal
En este caso diría se alude a un dominio [dominio proteico; a una proteína en sí misma] de unión a ligando C-terminal.
Por ejemplo,
MR tienen tres grandes dominios funcionales: un dominio N-terminal (NTD), seguido por un dominio de unión al ADN central (DBD), y un dominio de unión a ligando C-terminal (LBD),...
https://www.google.es/url?sa=t&source=web&rct=j&url=https://...
Así, tiene sentido en tu original,
fusion proteins including one or more N-terminus antigen binding subunits, a central Fc polypeptide core, and one or more C-terminus ligand proteins.
... Así como la continuación, aludiendo a las distintas subunidades;
(...) the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL,...
Por ejemplo,
MR tienen tres grandes dominios funcionales: un dominio N-terminal (NTD), seguido por un dominio de unión al ADN central (DBD), y un dominio de unión a ligando C-terminal (LBD),...
https://www.google.es/url?sa=t&source=web&rct=j&url=https://...
Así, tiene sentido en tu original,
fusion proteins including one or more N-terminus antigen binding subunits, a central Fc polypeptide core, and one or more C-terminus ligand proteins.
... Así como la continuación, aludiendo a las distintas subunidades;
(...) the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL,...
5 hrs
Clara Bugallo
Argentina
Argentina
Native in Spanish
Argentina
Translator and proofreader
Native in: Spanish (Variant: Argentine) 
Works in: English to Spanish
proteína ligando
Justamente estoy haciendo una traducción donde me apareció la palabra "ligand" para traducir y en el diccionario de medicina me dice que es una molécula.
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