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Glossary entry

English term or phrase:

(...) which operates benzyl penicillin.

English answer:

Benzylpenicillin is active against Gram-positive org

Added to glossary by Sofia Margherita Salvini
Sep 14, 2020 20:58
3 yrs ago
38 viewers *
English term

(...) which operates benzyl penicillin.

English Science Medical (general)
The drug is not destroyed in the acidic environment of the stomach, it is well absorbed when taken orally.
It is active against Gram-positive microorganisms, which operates benzyl penicillin.
Responses
4 Benzylpenicillin is active against Gram-positive org
5 -1 The drug is composed of benzyl penicillin.
3 ... it means the drug can work with benzyl penicillin...

Discussion

Ravi Kumar Sep 15, 2020:
All oral penicillins are best given on an empty stomach to avoid the absorption delay caused by food. The view is generally held that when given by mouth penicillin is destroyed by stomach acid and in consequence only very small amounts can be detected in the urine.1 In contrast, when given by intravenous or intramuscular injection, urine recoveries of penicillin were reported to average approximately 60 per cent.

Note: Information is missing to understand the complete details
Sofia Margherita Salvini (asker) Sep 14, 2020:
The text is about ampicillin. The sentence doesn’t make sense to me, I think I’ll ask the agency to check and correct it. Thank you!
Sofia Margherita Salvini (asker) Sep 14, 2020:
The text is about ampicillin. The sentence doesn’t make sense to me, I think I’ll ask the agency to check and correct it. Thank you!
philgoddard Sep 14, 2020:
"Against which benzylpenicillin operates" would fit. What is the drug? It may be possible to find the correct version online.
Helena Chavarria Sep 14, 2020:
I agree with you the sentence doesn't make sense.

Benzylpenicillin (penicillin G) and phenoxymethylpenicillin (penicillin V) are active against many aerobic Gram-positive bacteria

https://www.sciencedirect.com/topics/neuroscience/benzylpeni...

Responses

13 hrs
Selected

Benzylpenicillin is active against Gram-positive org


Change sentence around

Clinical advice concerning the shortage of benzylpenicillin - TGAwww.tga.gov.au › files › alerts-medicine-benpen-110928
DOC
20 Sep 2011 - Narrow-spectrum penicillins such as benzylpenicillin, procaine penicillin and benzathine penicillin are active against Gram-positive organisms ...

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Note added at 13 hrs (2020-09-15 10:03:23 GMT)
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that should read


Gram-positive microorganisms

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Note added at 13 hrs (2020-09-15 10:04:24 GMT)
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Benzylpenicillin - DrugBankwww.drugbank.ca › drugs
Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the ...

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Note added at 13 hrs (2020-09-15 10:04:56 GMT)
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Penicillins | Treatment summary | BNF content published by ...bnf.nice.org.uk › treatment-summary › penicillins
Ampicillin is active against certain Gram-positive and Gram-negative organisms but is inactivated by penicillinases including those produced by Staphylococcus ...

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Note added at 13 hrs (2020-09-15 10:07:46 GMT)
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UNASYN (ampicillin sodium/sulbactam sodium) - FDAwww.accessdata.fda.gov › drugsatfda_docs › label
PDF
Ampicillin is similar to benzyl penicillin in its bactericidal action against susceptible organisms ... Gram-Positive Bacteria: Staphylococcus aureus (beta-lactamase and non-beta-lactamase ... should not be reconstituted together due to the in vitro inactivation of aminoglycosides by ... work area, such as a laminar flow hood.
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you a lot!"
8 mins

... it means the drug can work with benzyl penicillin...

:) ...against Gram-positive microorganisms.
Note from asker:
Thank you! I'm not sure about the structure of the sentence though... It doesn't make sense to me
Something went wrong...
-1
16 mins

The drug is composed of benzyl penicillin.

FYI penicillin G (benzyl penicillin) has higher acid stability and it works best on gram-positive bacteria.

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Note added at 24 mins (2020-09-14 21:23:18 GMT)
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Where was it published?
Note from asker:
Thank you! I'm not sure about the structure of the sentence though... It doesn't make sense to me
Peer comment(s):
disagree Cilian O'Tuama : How can you be 100% confident if the ST is faulty? Naw. Am changing from neutral.
2 hrs
Something went wrong...
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