Glossary entry (derived from question below)
Portuguese term or phrase:
fármaco livre
English translation:
free drug
Added to glossary by
ServingMed.com
Dec 5, 2016 08:08
7 yrs ago
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Portuguese term
fármaco livre
Portuguese to English
Other
Medical (general)
pharmacology
Os valores médios da depuração para indivíduos com insuficiência hepática leve, moderada e grave foram respectivamente 74%, 64% e 53%, dos valores observados em indivíduos normais e saudáveis.
As depurações médias para fármaco livre foram respectivamente 59%, 51% e 32%, dos valores observados em indivíduos normais e saudáveis.
Are they referring to drug-free or free drug in this context?
Many thanks,
Juliette
As depurações médias para fármaco livre foram respectivamente 59%, 51% e 32%, dos valores observados em indivíduos normais e saudáveis.
Are they referring to drug-free or free drug in this context?
Many thanks,
Juliette
Proposed translations
(English)
4 +2 | free drug | Rafael Sousa Brazlate |
3 +3 | unbound drug | Luciano Eduardo de Oliveira |
Proposed translations
+2
24 mins
Selected
free drug
Luciano's explanation is perfect from the technical standpoint, but from the terminological one the best choice is free drug, since it is the term used to refer to unbound drug.
http://medical-dictionary.thefreedictionary.com/free drug
http://medical-dictionary.thefreedictionary.com/free drug
4 KudoZ points awarded for this answer.
Comment: "Thanks1"
+3
9 mins
unbound drug
Notavelmente, é a fração não-ligada (ou livre) que exibe efeitos farmacológicos. É também a fração que pode ser metabolizada e/ou excretada.
https://pt.wikipedia.org/wiki/Ligação_a_proteínas_plasmática...
Notably, it is the unbound fraction which exhibits pharmacologic effects. It is also the fraction that may be metabolized and/or excreted.
https://en.wikipedia.org/wiki/Plasma_protein_binding
http://medical-dictionary.thefreedictionary.com/unbound drug
https://pt.wikipedia.org/wiki/Ligação_a_proteínas_plasmática...
Notably, it is the unbound fraction which exhibits pharmacologic effects. It is also the fraction that may be metabolized and/or excreted.
https://en.wikipedia.org/wiki/Plasma_protein_binding
http://medical-dictionary.thefreedictionary.com/unbound drug
Peer comment(s):
agree |
Marjolein Snippe
: You beat me to it :)
8 mins
|
agree |
Margarida Ataide
42 mins
|
agree |
Clauwolf
3 hrs
|
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