https://www.proz.com/personal-glossaries/entry/2767121-nicked-circle-relaxed-circle-during-extraction-of-plasmid-dna-from-the-bacterial-cell-one-strand-of-the-dna-becomes-nicked

Nicked circle (relaxed circle) During extraction of plasmid DNA from the bacterial cell, one strand of the DNA becomes nicked

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Language pair:English
Definition / notes:This relaxes the torsional strain needed to maintain supercoiling, producing the familiar form of plasmid
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