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autonomie d’analyse
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Glossary entry

French term or phrase:

déreglé

English translation:

disrupted or anarchic proliferation

Added to glossary by Drmanu49
May 22, 2009 22:52
14 yrs ago
2 viewers *
French term

déreglé

French to English Medical Medical (general)
Que penser alors de la « nature » qui témoigne à la fois d’un élan de vie dont on s’émerveille à juste titre et qui est capable, dans le même élan, d’apporter la mort par prolifération d’une vie envahissante et déréglée ? I know it means 'gone awry' but can't think of a good combination of adjectives in this sentence.
Proposed translations (English)
4 +1 disrupted or anarchic proliferation
3 +2 disordered/disarranged
4 +1 out of control
4 unsettled
4 uncontrolled
3 care free
3 haphazard
Change log

May 22, 2009 23:02: Emanuela Galdelli changed "Term asked" from "déreglé (dans ce contexte)" to "déreglé"

Jun 3, 2009 17:39: Drmanu49 changed "Edited KOG entry" from "<a href="/profile/569588">ormiston's</a> old entry - "disrupted or anarchic proliferation"" to ""disrupted or anarchic proliferation""

Discussion

Gabrielle Leyden May 24, 2009:
adjectives You don't have to stick with adjectives. "The proliferation of invasive cells that have (cells) or has (proliferation) gone amok" (or talking about proliferation that has gone awry) would get the same idea across. Just a reaction to you comment about "not finding the adjectives you need."
Michael Lotz May 23, 2009:
thanks for context appreciate the additional information, which confirms my first take on it. See my additional note for why "rogue" I think is not right here, although perfectly fine for another context.
ormiston (asker) May 23, 2009:
context as requested À l’opposé, l’angiogenèse, quand elle se développe de façon anarchique mais tout aussi « naturelle », produit encore de la vie, mais une vie dont on peut dire qu’elle progresse « contre la vie ». En assurant la multiplication des cellules cancéreuses, elle leur permet de dévorer les cellules saines et de se répandre dans l’organisme grâce aux vaisseaux sanguins qu’elle fabrique ou qu’elle détourne à leur profit. Ce phénomène est également naturel mais, en tant que tel, il est mortel si l’on n’intervient pas. La voracité des cellules cancéreuses est comparable à l’attitude des vainqueurs qui tuaient les vaincus en leur imposant une inanition totale.
ormiston (asker) May 23, 2009:
more context yes it's about the proliferation of cancer cells. Sorry, it is so easy to presume it's clear! Diane has picked up on my problem of how to put it. Could 'rogue' possibly work as an adjective ? not medical enough ? Would love your feedback...

Proposed translations

+1
10 hrs
Selected

disrupted or anarchic proliferation

Cancer can occur in any tissue. It is the result of a disruption in the systems controlling cell growth, which leads to incessant anarchic proliferation of ...
www.inserm.fr/en/questionsdesante/dossiers/cancer/ - 37k

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Note added at 10 hrs (2009-05-23 09:28:28 GMT)
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Anarchic cell proliferation, observed in some leukemia and in breast and ovarian cancers, has .... association was found to be completely disrupted by 10 M .... of the Ras signalling pathway in human breast cancer cells ...
cmbi.bjmu.edu.cn/news/report/2004/ras/view/81.pdf
Note from asker:
Here I used 'anarchic' I should say
Peer comment(s):
agree Raya Mansour : adequate solution I think
1 day 10 hrs
Thank you Raya.
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "this is what I finally used - thanks to all"
4 mins
French term (edited): déreglé (dans ce contexte)

unsettled

my take, in this context
Something went wrong...
+2
17 mins

disordered/disarranged

#
hyperammonemia (metabolic disorder) -- Britannica Online Encyclopedia
- [ Traducir esta página ]
Britannica online encyclopedia article on hyperammonemia (metabolic disorder), disorder due to excessive amounts of ammonia in the blood caused by a genetic ...
www.britannica.com/EBchecked/topic/670067/hyperammonemia - 44k - En caché - Páginas similares
#
WikiAnswers - What is the a linear metabolic pathway
- [ Traducir esta página ]
What is metabolic disorder of cerebrosides? Difference between a linear and cyclic metabolic pathway? The linear pathway of is the first metabolic pathway ...
wiki.answers.com/Q/What_is_the_a_linear_metabolic_pathway - 45k - En caché - Páginas similares
#
Learn more about metabolic pathway | Eureka! Science News
- [ Traducir esta página ]
Fructose, on the other hand, enters this metabolic pathway downstream, bypassing the ... largest DNA scan for autism uncovers new gene variant for disorder ...
esciencenews.com/dictionary/metabolic.pathway - 22k - En caché - Páginas similares
#
Medical Hypotheses : The urea cycle as a source of nitric oxide ...
- [ Traducir esta página ]
In this way, diabetes mellitus may be the only metabolic disorder in which the disease state is in no way related to any metabolic pathway. ...
linkinghub.elsevier.com/retrieve/pii/S0306987798902584 - Páginas similares
de JA Bauer - 1998 - Artículos relacionados - Las 6 versiones
Peer comment(s):
agree Kim Metzger : But I don't see the relevance of your references about metabolic disorders.
28 mins
agree Helen Shiner : About to post the same as Kim
51 mins
neutral Drmanu49 : not used in this context (cancer)
10 hrs
Something went wrong...
6 hrs

uncontrolled

My version because:
Out of control implies there was control in the first place, which there isn't in this case. Uncontrolled is from the onset without control.


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Note added at 6 hrs (2009-05-23 04:58:28 GMT)
--------------------------------------------------

perhaps something like:
uncontrolled and invasive (rather than invasive and uncontrolled which doesn't flow so well)
Something went wrong...
+1
9 mins
French term (edited): déreglé (dans ce contexte)

out of control

would make sense, but more context is needed to be sure

--------------------------------------------------
Note added at 10 minutes (2009-05-22 23:02:17 GMT)
--------------------------------------------------

what is the subject and direction of the whole document ?

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Note added at 1 heure (2009-05-23 00:12:22 GMT)
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are we in the neoplastic sphere with out of control, unregulated cancer cell growth, or somewhere else ?
the sentences given lead me to think of that but perhaps that is not it....

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Note added at 12 heures (2009-05-23 11:17:34 GMT)
--------------------------------------------------

One needs to express the escape from usual constraints on cell growth and orderliness of cell division with feedback loops that control the angiogenesis for healthy cells. This situation is entirely the contrary. One can have linguistic preferences for alternative formulations but the idea of "out of control" walks the line between overly "medical" and "scientific" vocabulary and inaccurate metaphors, however poetic or good otherwise.
"Out of control" does impl there was control before, as indeed there was:
normal homeostatic mechanisms for cell division and blood supply save us from cancerous growth and blood vessel proliferation when such proliferation is not necessary....Without going into "derepression of oncogene" talk, it does make sense.
Peer comment(s):
agree Lionel_M (X)
3 hrs
merci Lionel_M
Something went wrong...
14 hrs

care free

The context talks metaphoricaly of the two sides of nature.
Care free appears to fit in the nuance of the situation. It means awry, not concerned about regulation, essentially care free
Something went wrong...
21 hrs

haphazard

Not my field, I just found the question interesting!

Or maybe 'disruptive'?

Both these refs includee the word 'haphazard' and the first also contains 'disruptive' and 'rebellious'...
Reference:

http://www.truthaboutwellness.com/cancer.html

http://creationwiki.org/Cancer

Something went wrong...
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