English to Italian Medical Biology (-tech,-chem,micro-)

False novelty called
Infrequently, XX® can report false novelties to the end user. Out of 616 analyzed samples (8624 allele calls) in the XX Performance Evaluation Study (PES) set, 31 novelties were reported (0.375% of all allele calls). Note, that the PES set contains reference cell lines and more homozygous, rare or otherwise challenging loci compared to a typical patient population. Out of these expected novelties, 15 were deemed to be false and the result of software issues based on manual investigation. Loci with obvious quality issues (namely, high imbalance) were excluded from the list as these are not considered purely algorithm related limitations. Note, that the vast majority of these false novelties can be eliminated by manual inspection of the results in XXX® by a trained user. The observed false novelties were the following:

Result called by XX®
Correct result
Was the expected call homozygous?
Sequencing chemistry
Number of observed cases
% of allele calls