Glossary entry (derived from question below)
German term or phrase:
nach Spiegel
English translation:
according to levels
Added to glossary by
Jessica Klingberg
Apr 26, 2018 01:04
6 yrs ago
7 viewers *
German term
nach Spiegel
German to English
Medical
Medical: Pharmaceuticals
Prescription of pharmaceuticals
This comes from a medical report:
- Unverzüglich erfolgte bei V.a. PD-assoziierte Peritonitis die Einleitung einer dualen i.p. Antibiose mit Vancomycin und Gentamycin, nach Spiegel.
- Vancomycin hydrochlorid z.B. VANCOMYCIN Eberth 1 g Troc, i.p. nach Spiegel
- Gentamicin sulfat, z.B. REFOBACIN 80 Injektionslös, i.p. nach Spiegel
Thank you for your help.
- Unverzüglich erfolgte bei V.a. PD-assoziierte Peritonitis die Einleitung einer dualen i.p. Antibiose mit Vancomycin und Gentamycin, nach Spiegel.
- Vancomycin hydrochlorid z.B. VANCOMYCIN Eberth 1 g Troc, i.p. nach Spiegel
- Gentamicin sulfat, z.B. REFOBACIN 80 Injektionslös, i.p. nach Spiegel
Thank you for your help.
Proposed translations
+3
2 hrs
Selected
according to level
Gentamicin and vancomycin are antibiotics whose blood level (concentration) may need to be monitored:
"Patients with a creatinine clearance of <20ml/min should have gentamicin levels taken every 48 hours, and receive their next dose when levels fall to <1mg/L."
https://www.pharmaceutical-journal.com/learning/learning-art...
"Patients with a creatinine clearance of <20ml/min should have gentamicin levels taken every 48 hours, and receive their next dose when levels fall to <1mg/L."
https://www.pharmaceutical-journal.com/learning/learning-art...
Peer comment(s):
agree |
Marga Shaw
: 'Continue IP Vancomycin and Gentamicin according to levels.' www.meht.nhs.uk/EasysiteWeb/getresource.axd?AssetID=13420&t...
4 hrs
|
Many thanks, Marga.
|
|
agree |
Anne Schulz
5 hrs
|
Many thanks, Anne.
|
|
agree |
Elif Baykara Narbay
13 hrs
|
Many thanks, Elif.
|
4 KudoZ points awarded for this answer.
Comment: "This is the answer I chose to use, although I'd still like to thank andres-larsen for his valuable contribution."
35 mins
according to/in line with medical records
not sure if this works but might get the ball rolling
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Note added at 36 mins (2018-04-26 01:41:07 GMT)
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not much more than a guess here
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Note added at 1 hr (2018-04-26 02:28:54 GMT)
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"medical records on file" at a stretch
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Note added at 1 hr (2018-04-26 02:29:22 GMT)
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but I'm guessing
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Note added at 36 mins (2018-04-26 01:41:07 GMT)
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not much more than a guess here
--------------------------------------------------
Note added at 1 hr (2018-04-26 02:28:54 GMT)
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"medical records on file" at a stretch
--------------------------------------------------
Note added at 1 hr (2018-04-26 02:29:22 GMT)
--------------------------------------------------
but I'm guessing
+1
2 days 16 hrs
subject to [gentamicin / vancomycin] concentrations / levels [therapeutic drug] monitoring <TDM>
in line with Lancashireman:
subject to [gentamicin / vancomycin] concentrations / levels [therapeutic drug] monitoring <TDM>
sources:
The Role of Monitoring Gentamicin Levels in Patients ... - ResearchGate
https://www.researchgate.net/.../259566864_The_Role_of_Monit...
Dec 21, 2017 - Full-text (PDF) | There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients receiving this ... In 17 (26%) patients receiving extended gentamicin therapy, day-5 gentamicin levels were not significantly related to peritonitis cure.
The role of monitoring vancomycin levels in patients with peritoneal ...
europepmc.org/articles/pmc4406318
S Stevenson - 2015 -
Keywords: Kidney failure, chronic outcomes, peritoneal dialysis, peritonitis, therapeutic drug monitoring, vancomycin ... When antibiotics are administered intermittently via the IP route, ongoing effective eradication of peritoneal organisms during non-antibiotic PD exchanges requires back-diffusion of drug from the serum ...
The Role of Monitoring Gentamicin Levels in Patients with Gram ...
www.pdiconnect.com/content/34/2/219.abstract
W Tang - 2014 -
Background: There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients ... between measured serum gentamicin levels on day 2 following initial empiric antibiotic therapy and subsequent clinical outcomes of confirmed gram-negative peritonitis.
Intraperitoneal Vancomycin Concentrations During Peritoneal Dialysis ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525447/
R Fish - 2012 -
Reagents from Roche Diagnostics (Mannheim, Germany) for online therapeutic drug monitoring were used for vancomycin measurements, and the assay was run on the Roche Modular Analytics P module platform. The sampling system uses capacitance liquid level sensing technology. The reagents consisted of 2 ...
Therapeutic drug monitoring of antimicrobials - NCBI - NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248253/
JA Roberts - 2012 -
Therapeutic drug monitoring of aminoglycosides (e.g. gentamicin, tobramycin and amikacin) has become standard clinical practice. Whilst the purpose of this .... Monitoring of vancomycin peak concentration is no longer considered necessary given the strong correlation between trough concentrations and AUC0–24/MIC.
Therapeutic drug monitoring - Public Health Ontario
https://www.publichealthontario.ca/.../ASP_Strategy_Therapeu...
infective therapeutic drug monitoring involves aminoglycosides (e.g., gentamicin, tobramycin, amikacin) and vancomycin. There are definite associations between toxicity and aminoglycoside trough serum levels and between therapeutic efficacy and peak serum levels.1. Patients on aminoglycoside therapy should have ...
subject to [gentamicin / vancomycin] concentrations / levels [therapeutic drug] monitoring <TDM>
sources:
The Role of Monitoring Gentamicin Levels in Patients ... - ResearchGate
https://www.researchgate.net/.../259566864_The_Role_of_Monit...
Dec 21, 2017 - Full-text (PDF) | There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients receiving this ... In 17 (26%) patients receiving extended gentamicin therapy, day-5 gentamicin levels were not significantly related to peritonitis cure.
The role of monitoring vancomycin levels in patients with peritoneal ...
europepmc.org/articles/pmc4406318
S Stevenson - 2015 -
Keywords: Kidney failure, chronic outcomes, peritoneal dialysis, peritonitis, therapeutic drug monitoring, vancomycin ... When antibiotics are administered intermittently via the IP route, ongoing effective eradication of peritoneal organisms during non-antibiotic PD exchanges requires back-diffusion of drug from the serum ...
The Role of Monitoring Gentamicin Levels in Patients with Gram ...
www.pdiconnect.com/content/34/2/219.abstract
W Tang - 2014 -
Background: There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients ... between measured serum gentamicin levels on day 2 following initial empiric antibiotic therapy and subsequent clinical outcomes of confirmed gram-negative peritonitis.
Intraperitoneal Vancomycin Concentrations During Peritoneal Dialysis ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525447/
R Fish - 2012 -
Reagents from Roche Diagnostics (Mannheim, Germany) for online therapeutic drug monitoring were used for vancomycin measurements, and the assay was run on the Roche Modular Analytics P module platform. The sampling system uses capacitance liquid level sensing technology. The reagents consisted of 2 ...
Therapeutic drug monitoring of antimicrobials - NCBI - NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248253/
JA Roberts - 2012 -
Therapeutic drug monitoring of aminoglycosides (e.g. gentamicin, tobramycin and amikacin) has become standard clinical practice. Whilst the purpose of this .... Monitoring of vancomycin peak concentration is no longer considered necessary given the strong correlation between trough concentrations and AUC0–24/MIC.
Therapeutic drug monitoring - Public Health Ontario
https://www.publichealthontario.ca/.../ASP_Strategy_Therapeu...
infective therapeutic drug monitoring involves aminoglycosides (e.g., gentamicin, tobramycin, amikacin) and vancomycin. There are definite associations between toxicity and aminoglycoside trough serum levels and between therapeutic efficacy and peak serum levels.1. Patients on aminoglycoside therapy should have ...
Peer comment(s):
agree |
Lancashireman
: At 27 mins. Duplicated at 2 hrs.
5 mins
|
Thanks, Lancashireman, you are right!
|
Reference comments
27 mins
Reference:
therapeutic drug monitoring TDM > Arzneimittelspiegelbestimmung
The Role of Monitoring Gentamicin Levels in Patients ... - ResearchGate
https://www.researchgate.net/.../259566864_The_Role_of_Monit...
Dec 21, 2017 - Full-text (PDF) | There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients receiving this ... In 17 (26%) patients receiving extended gentamicin therapy, day-5 gentamicin levels were not significantly related to peritonitis cure.
The role of monitoring vancomycin levels in patients with peritoneal ...
europepmc.org/articles/pmc4406318
S Stevenson - 2015 -
Keywords: Kidney failure, chronic outcomes, peritoneal dialysis, peritonitis, therapeutic drug monitoring, vancomycin ... When antibiotics are administered intermittently via the IP route, ongoing effective eradication of peritoneal organisms during non-antibiotic PD exchanges requires back-diffusion of drug from the serum ...
The Role of Monitoring Gentamicin Levels in Patients with Gram ...
www.pdiconnect.com/content/34/2/219.abstract
W Tang - 2014 -
Background: There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients ... between measured serum gentamicin levels on day 2 following initial empiric antibiotic therapy and subsequent clinical outcomes of confirmed gram-negative peritonitis.
Intraperitoneal Vancomycin Concentrations During Peritoneal Dialysis ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525447/
R Fish - 2012 -
Reagents from Roche Diagnostics (Mannheim, Germany) for online therapeutic drug monitoring were used for vancomycin measurements, and the assay was run on the Roche Modular Analytics P module platform. The sampling system uses capacitance liquid level sensing technology. The reagents consisted of 2 ...
dict.cc Wörterbuch :: therapeutic drug monitoring :: Deutsch-Englisch ...
https://www.dict.cc/englisch.../therapeutic drug monitoring....
Übersetzung(en) tabellarisch anzeigen | immer » Übersetzungen mit gleichem Wortanfang » therapeutic | drug | monitoring · therapeutic drug monitoring <TDM> · Arzneimittelspiegelbestimmung {f} med. therapeutisches Drug-Monitoring {n} <TDM> med. Medikamentenspiegelbestimmung {f} med. pharm.
TDM - Therapeutic Drug Monitoring ... - Labor Lademannbogen
www.labor-lademannbogen.de/analysen/analysen-spektrum/.../t...
TDM. Therapeutic Drug Monitoring, Medikamentenspiegelbestimmung, Drug Monitoring. Material. je nach Wirkstoff und Fragestellung: - Serum/Plasma. - EDTA-Blut. - Sonstige. Klinische Relevanz. - Individuelle Dosisanpassung mit dem Ziel optimaler Wirkspiegel. - Unterversorgung / Wirkverlust erkennen. - Überdosierung ...
Therapeutisches Drug Monitoring (TDM) - Labor Lademannbogen
www.labor-lademannbogen.de/.../therapeutisches-drug-monitor...
Das Therapeutische Drug Monitoring (TDM) ist die Bestimmung von Konzentrationen (Spiegel) von therapeutisch verabreichten Substanzen (Arzneimitteln) in ... Nach Medikationsbeginn und auch nach jeder Dosis-Änderung müssen mindestens 4-5 Halbwertszeiten vergangen sein, bis dieser Zustand erreicht ist.
--------------------------------------------------
Note added at 34 mins (2018-04-26 01:38:53 GMT)
--------------------------------------------------
Therapeutic drug monitoring of antimicrobials - NCBI - NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248253/
JA Roberts - 2012 -
Therapeutic drug monitoring of aminoglycosides (e.g. gentamicin, tobramycin and amikacin) has become standard clinical practice. Whilst the purpose of this .... Monitoring of vancomycin peak concentration is no longer considered necessary given the strong correlation between trough concentrations and AUC0–24/MIC.
Therapeutic drug monitoring - Public Health Ontario
https://www.publichealthontario.ca/.../ASP_Strategy_Therapeu...
infective therapeutic drug monitoring involves aminoglycosides (e.g., gentamicin, tobramycin, amikacin) and vancomycin. There are definite associations between toxicity and aminoglycoside trough serum levels and between therapeutic efficacy and peak serum levels.1. Patients on aminoglycoside therapy should have ...
Therapeutisches Drug-Monitoring (TDM) - Roche Diagnostics
www.roche-diagnostics.ch/.../02TDM-Therapeutic-drug-monitor...
TDM: vom therapeutischen Drug-Monitoring hin zum thera- peutischen .... gende Nebenwirkungen herbeiführen: Antiasthmatika. Theophyllin. Antibiotika. Amikacin. Gentamicin. Vancomycin. Tobramycin. Antimanika. Carbamazepin. Lithium ..... Der C2-Spiegel, zwei Stunden nach Verabreichung von Cyclospo- rin, stellt den ...
TDM-Handbuch IKP HRO 2016 - Institut für Klinische Pharmakologie
https://ipharma.med.uni-rostock.de/.../TDM-Handbuch_IKP_HRO_...
Mar 1, 2016 - 1.3.2 TDM-Eilanalytik: Eil- und Notfallproben für die Analyten der TDM-Routineanalytik - 5 - ..... Vancomycin-Talspiegel. EDTA 2 ml ... Antibiotika. Gentamicin. 1). 15 - 25 mg/l. Maximum 0,5 h nach Ende der. Infusion über 0,5 h. < 1 mg/l. Minimum direkt vor nächster Dosis. Tobramycin. 1). 15 - 25 mg/l.
--------------------------------------------------
Note added at 36 mins (2018-04-26 01:40:50 GMT)
--------------------------------------------------
Therapeutisches Drug-Monitoring von Antibiotika - Hygel
www.hygel.de/.../Therapeutisches_Drug-Monitoring_von_Antibi...
Apr 24, 2014 - Therapeutisches Drugmonitoring (TDM) von Antibiotika ist bereits ... Spiegelkontrolle nach Erreichen des vermuteten Steady-State ... Piperacillin (auch anzufordern bei. Gabe von Piperacillin/Tazobactam. (Tazobac®)). ▻ Meropenem. ▻ Tobramycin. ▻ Gentamicin. ▻ Vancomycin. ▻ Fosfomycin. Messung ...
https://www.researchgate.net/.../259566864_The_Role_of_Monit...
Dec 21, 2017 - Full-text (PDF) | There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients receiving this ... In 17 (26%) patients receiving extended gentamicin therapy, day-5 gentamicin levels were not significantly related to peritonitis cure.
The role of monitoring vancomycin levels in patients with peritoneal ...
europepmc.org/articles/pmc4406318
S Stevenson - 2015 -
Keywords: Kidney failure, chronic outcomes, peritoneal dialysis, peritonitis, therapeutic drug monitoring, vancomycin ... When antibiotics are administered intermittently via the IP route, ongoing effective eradication of peritoneal organisms during non-antibiotic PD exchanges requires back-diffusion of drug from the serum ...
The Role of Monitoring Gentamicin Levels in Patients with Gram ...
www.pdiconnect.com/content/34/2/219.abstract
W Tang - 2014 -
Background: There is limited available evidence regarding the role of monitoring serum gentamicin concentrations in peritoneal dialysis (PD) patients ... between measured serum gentamicin levels on day 2 following initial empiric antibiotic therapy and subsequent clinical outcomes of confirmed gram-negative peritonitis.
Intraperitoneal Vancomycin Concentrations During Peritoneal Dialysis ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525447/
R Fish - 2012 -
Reagents from Roche Diagnostics (Mannheim, Germany) for online therapeutic drug monitoring were used for vancomycin measurements, and the assay was run on the Roche Modular Analytics P module platform. The sampling system uses capacitance liquid level sensing technology. The reagents consisted of 2 ...
dict.cc Wörterbuch :: therapeutic drug monitoring :: Deutsch-Englisch ...
https://www.dict.cc/englisch.../therapeutic drug monitoring....
Übersetzung(en) tabellarisch anzeigen | immer » Übersetzungen mit gleichem Wortanfang » therapeutic | drug | monitoring · therapeutic drug monitoring <TDM> · Arzneimittelspiegelbestimmung {f} med. therapeutisches Drug-Monitoring {n} <TDM> med. Medikamentenspiegelbestimmung {f} med. pharm.
TDM - Therapeutic Drug Monitoring ... - Labor Lademannbogen
www.labor-lademannbogen.de/analysen/analysen-spektrum/.../t...
TDM. Therapeutic Drug Monitoring, Medikamentenspiegelbestimmung, Drug Monitoring. Material. je nach Wirkstoff und Fragestellung: - Serum/Plasma. - EDTA-Blut. - Sonstige. Klinische Relevanz. - Individuelle Dosisanpassung mit dem Ziel optimaler Wirkspiegel. - Unterversorgung / Wirkverlust erkennen. - Überdosierung ...
Therapeutisches Drug Monitoring (TDM) - Labor Lademannbogen
www.labor-lademannbogen.de/.../therapeutisches-drug-monitor...
Das Therapeutische Drug Monitoring (TDM) ist die Bestimmung von Konzentrationen (Spiegel) von therapeutisch verabreichten Substanzen (Arzneimitteln) in ... Nach Medikationsbeginn und auch nach jeder Dosis-Änderung müssen mindestens 4-5 Halbwertszeiten vergangen sein, bis dieser Zustand erreicht ist.
--------------------------------------------------
Note added at 34 mins (2018-04-26 01:38:53 GMT)
--------------------------------------------------
Therapeutic drug monitoring of antimicrobials - NCBI - NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248253/
JA Roberts - 2012 -
Therapeutic drug monitoring of aminoglycosides (e.g. gentamicin, tobramycin and amikacin) has become standard clinical practice. Whilst the purpose of this .... Monitoring of vancomycin peak concentration is no longer considered necessary given the strong correlation between trough concentrations and AUC0–24/MIC.
Therapeutic drug monitoring - Public Health Ontario
https://www.publichealthontario.ca/.../ASP_Strategy_Therapeu...
infective therapeutic drug monitoring involves aminoglycosides (e.g., gentamicin, tobramycin, amikacin) and vancomycin. There are definite associations between toxicity and aminoglycoside trough serum levels and between therapeutic efficacy and peak serum levels.1. Patients on aminoglycoside therapy should have ...
Therapeutisches Drug-Monitoring (TDM) - Roche Diagnostics
www.roche-diagnostics.ch/.../02TDM-Therapeutic-drug-monitor...
TDM: vom therapeutischen Drug-Monitoring hin zum thera- peutischen .... gende Nebenwirkungen herbeiführen: Antiasthmatika. Theophyllin. Antibiotika. Amikacin. Gentamicin. Vancomycin. Tobramycin. Antimanika. Carbamazepin. Lithium ..... Der C2-Spiegel, zwei Stunden nach Verabreichung von Cyclospo- rin, stellt den ...
TDM-Handbuch IKP HRO 2016 - Institut für Klinische Pharmakologie
https://ipharma.med.uni-rostock.de/.../TDM-Handbuch_IKP_HRO_...
Mar 1, 2016 - 1.3.2 TDM-Eilanalytik: Eil- und Notfallproben für die Analyten der TDM-Routineanalytik - 5 - ..... Vancomycin-Talspiegel. EDTA 2 ml ... Antibiotika. Gentamicin. 1). 15 - 25 mg/l. Maximum 0,5 h nach Ende der. Infusion über 0,5 h. < 1 mg/l. Minimum direkt vor nächster Dosis. Tobramycin. 1). 15 - 25 mg/l.
--------------------------------------------------
Note added at 36 mins (2018-04-26 01:40:50 GMT)
--------------------------------------------------
Therapeutisches Drug-Monitoring von Antibiotika - Hygel
www.hygel.de/.../Therapeutisches_Drug-Monitoring_von_Antibi...
Apr 24, 2014 - Therapeutisches Drugmonitoring (TDM) von Antibiotika ist bereits ... Spiegelkontrolle nach Erreichen des vermuteten Steady-State ... Piperacillin (auch anzufordern bei. Gabe von Piperacillin/Tazobactam. (Tazobac®)). ▻ Meropenem. ▻ Tobramycin. ▻ Gentamicin. ▻ Vancomycin. ▻ Fosfomycin. Messung ...
Peer comments on this reference comment:
agree |
Lancashireman
: level/concentrations: you should have posted this as an answer
12 hrs
|
Thanks, Lancashireman, I will!
|
Discussion
I'm pretty sure that this phrase is short for "(Dosierung) nach Spiegelbestimmung" because of its usage.
Similar to my usage of "in quotes" below - a very informal version of "in quotation marks," or in British English "in inverted commas."
http://www.kh-cirs.de/faelle/juli15.html
https://static-content.springer.com/esm/art:10.1007/s00063-0...
Suggestion: "with therapeutic monitoring"
https://medicine.stonybrookmedicine.edu/system/files/SBUH Va...
http://medicalstaff.fraserhealth.ca/getattachment/Clinical-R...
https://www.idsociety.org/uploadedFiles/IDSA/Guidelines-Pati...
In line with andres-larsen's references under "therapeutic drug monitoring TDM > Arzneimittelspiegelbestimmung"
Another one: https://epub.uni-regensburg.de/28552/1/Dissertation_Onlineve...